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Ethopabate

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Ethopabate Basic information
Ethopabate Chemical Properties
  • Melting point:148-151 °C
  • Boiling point:426.1±35.0 °C(Predicted)
  • Density 1.180±0.06 g/cm3(Predicted)
  • storage temp.  0-6°C
  • pka14.12±0.70(Predicted)
  • Merck 13,3781
  • CAS DataBase Reference59-06-3(CAS DataBase Reference)
  • EPA Substance Registry SystemEthopabate (59-06-3)
Safety Information
  • Hazard Codes Xn
  • Risk Statements 22
  • WGK Germany 3
  • HS Code 2924296000
MSDS
Ethopabate Usage And Synthesis
  • Chemical PropertiesWhite to Off-White Solid
  • UsesA supplementary drug that improves the coccidiostatic effect of nicarbazin and amprolium in order to cure coccidiosis in chickens.
  • Usesantidepressant
  • Clinical UseEthopabate is only a narrow anticoccidial spectrum drug against Eimeria acervulina. It has no or only slight activity against E. maxima, E. necatrix, E. tenella or E. brunetti. Today, ethopabate is applied only in combination with amprolium and sulfonamide.
  • Molecular InteractionsEthopabate is a 2-substituted PABA derivative (=4-acetamido-2-ethoxybenzoic acid methylester) and functions as a prodrug. Its activity becomes potentiated by pyrimethamine and antagonised by the simultaneous administration of PABA. Thus, the mode of action of ethopabate is similar to that of sulfonamides or sulfones.
Ethopabate Preparation Products And Raw materials
Ethopabate(59-06-3)Related Product Information
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