PTEROLACTAM

Pterolactam can be isolated from Chrysanthemum coronarium L. Pterolactam derivates serval analogues that Mannich bases of amide with antifungal activities and cytotoxicity[1][2].

ChEBI: Pterolactam is a member of pyrrolidin-2-ones.

[1] Song MC, et al. Heterocyclic compounds from Chrysanthemum coronarium L. and their inhibitory activity on hACAT-1, hACAT-2, and LDL-oxidation. Arch Pharm Res. 2008 May;31(5):573-8. DOI:10.1007/s12272-001-1195-4
[2] Dascalu AE, et al. Design, synthesis and antifungal activity of pterolactam-inspired amide Mannich bases. Fitoterapia. 2020 Jun;143:104581. DOI:10.1016/j.fitote.2020.104581