Linderaspirone A

Linderaspirone A is a natural compound that can be isolated from the roots of Lindera aggregate. Linderaspirone A shows significant inhibitory effects on the production of prostaglandin E2 (PGE2),TNF-α, and IL-6 [1][2].

[1] Lin Chen, et al. Lindera cyclopentenedione intermediates from the roots of Lindera aggregate. RSC Adv. 2018 May 16;8(32):17898-17904. DOI:10.1039/c8ra03094d
[2] Chi-Su Yoon, et al. Effects of Compounds Isolated from Lindera erythrocarpa on Anti-Inflammatory and Anti-Neuroinflammatory Action in BV2 Microglia and RAW264.7 Macrophage. Int J Mol Sci. 2022 Jun 27;23(13):7122. DOI:10.3390/ijms23137122