2-IODOBENZOYL CHLORIDE

• palladium-catalyzed synthesis of carbomethoxy functional group-induced isoindolin-1-ones
• preparation of starting materials required for the synthesis of novel cyclic derivatives of pentavalent iodine, benziodazole oxides

88-67-5

609-67-6

General method: 2-iodobenzoic acid (1.0 mmol) was mixed with excess thionyl chloride (5 mL) and reacted at reflux for 2 hours. Upon completion of the reaction, the excess thionyl chloride was removed by vacuum concentration to give o-iodobenzoyl chloride in quantitative yield.