Staphylokinase, staphylococcus aureus (SAK) is a fibrin-specific plasminogen activator. Staphylokinase is an efficient, fibrin-selective thrombolytic agent[1].
Staphylokinase Recombinant produced in E.Coli is a non-glycosylated polypeptide chain containing 136 amino acids and having a molecular weight of 16kDa.
The Staphylokinase is purified by proprietary chromatographic techniques.
Staphylokinase (SAK) is a 136-amino acidenzymefrom Staphylococcus aureus. It is positively regulated by the "agr" gene regulator. It activates plasminogen, which in turn can degrade various host proteins during infection.
[1] Toul M, et al. Hidden Potential of Highly Efficient and Widely Accessible Thrombolytic Staphylokinase. Stroke. 2022 Oct;53(10):3235-3237. DOI:
10.1161/STROKEAHA.122.040219
