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Canrenone

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Canrenone Basic information
Canrenone Chemical Properties
  • Melting point:158-1600C
  • alpha D +24.5° (chloroform)
  • Boiling point:416.25°C (rough estimate)
  • Density 1.1236 (rough estimate)
  • refractive index 1.5000 (estimate)
  • storage temp. Store at RT
  • solubility DMSO: soluble20mg/mL, clear
  • form powder
  • color white to beige
  • optical activity[α]/D +17 to +24°, c = 1 in chloroform-d
  • Water Solubility 272.4ug/L(25 ºC)
  • CAS DataBase Reference976-71-6
  • NIST Chemistry ReferenceCanrenone(976-71-6)
Safety Information
  • Hazard Codes Xn,N
  • Risk Statements 40-51/53
  • Safety Statements 36/37-61
  • RIDADR UN 3077 9 / PGIII
  • WGK Germany 3
  • HS Code 29329990
Canrenone Usage And Synthesis
  • Chemical PropertiesPale yellow to pale Green Solid
  • UsesAldosterone antagonist. Diuretic
  • Usesantiinflammatory, glucocorticoid
  • brand nameLuvion.
  • World Health Organization (WHO)Canrenone, which has aldosterone antagonist activity, is a major metabolite of spironolactone and the major metabolite of potassium canrenoate. See WHO comments for potassium canrenoate and spironolactone.
  • Biological ActivityMineralocorticoid receptor antagonist. Active metabolite of spironolactone ((7a,17a)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21-carboxylic acid g-lactone ).
Canrenone Preparation Products And Raw materials
Canrenone(976-71-6)Related Product Information
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