Organic reagents
From early AD to mid-19 century, people mainly use the natural organic substance (such as animal and plant extracts) for qualitative analysis or quantitative analysis. From the second half of the 19th century to the 1920s, it had begun to appear of artificially synthetic organic reagent such as using potassium acetate xanthan for test of nickel, copper, and molybdenum; using morin for test of aluminum; using diazo coupling reaction for the detection of Nitrite; using α-β-nitroso naphthol for detection of cobalt; using dimethyglyoxime for nickel test.
After the proposal of the special-effects group in the 1930s and the proposal of theoretical analysis of functional groups theory in 1950s, people had carried out large-scale screen of organic reagents in search of special-effects analysis groups for different ions and had successfully synthesized a lot of agents of practical value (such as copper reagents, new copper agent, cadmium reagents, beryllium reagent, thorium reagents, etc.). Before the 1950s, the complex compound, in analytic chemistry, is mainly used in the aspects of the precipitation reaction of a binary chelate for the qualitative detection, precipitate isolation and gravimetric separation and other aspects. In the early 1950s and 1960, it is mainly in the form of complexometric titration. From the beginning of the late 1960s, the main focus has been moved to the photometric analysis. Meanwhile, it has been also developed of chelate organic solvent extraction.
8-hydroxy quinoline, hydrazones, oximes, hydroxamic acids, polyphenols, 1, 10-phenanthroline, phosphorus-oxygen extractant, β- diketones, triphenylmethane acid dye, xanthene dyes and azo dyes and other agents has all been widely studied and applied. On the other hand, the structural theoretical research (such as electronic effects, spatial effects and substituent effects) of the organic reagent can further facilitate the development of new-type organic reagents such as heterocyclic azo reagent. During this period, it has been also developed of monoazo chromotropic acid-type and disazo chromotropic acid-type reagent. During the mid-1970s, the chelating resin and adsorbents have achieved rapid development. Since the 1980s, Chinese researchers of analytical chemistry have made progress in the field of the synthesis and application of asymmetric disazo chromotropic acid.
Organic chemical reagents have wide application in analytic chemistry and are mainly used in solvents, precipitation agents, complexing agents, indicator, coloring reagent and surface active agent, etc. In order to adapt to a variety of analytical needs, sometimes it is required to purify certain reagents. For example, liquid organic reagent is often purified by distillation while solid substance is often purified through crystallization and sublimation. Substance having a high vapor pressure, namely having low purification boiling point and undergoing no decomposition under boiling temperature commonly applied atmospheric distillation; for less volatile and water-insoluble substance, namely having high purification point or undergoing decomposition under boiling temperature, we can apply vacuum distillation or steam distillation for purification of it.
Distillation is a commonly used method for laboratory purification of organic reagent. Conventional distillation apparatus generally comprises distiller, condenser and receiver, three parts with auxiliary section also containing heater, a thermometer, a wetted tube and cork.
- Structure:
- Chemical Name:N-MONOACETYL-4,4'-DIAMINODIPHENYL SULFONE
- CAS:565-20-8
- MF:C14H14N2O3S
- Structure:
- Chemical Name:PENTACHLOROTHIOPHENOL
- CAS:133-49-3
- MF:C6HCl5S
- Structure:
- Chemical Name:3-FLUOROBENZAMIDE
- CAS:455-37-8
- MF:C7H6FNO
- Structure:
- Chemical Name:3-Methoxybutyl acetate
- CAS:4435-53-4
- MF:C7H14O3
- Structure:
- Chemical Name:2-NITROPHENYL OCTYL ETHER
- CAS:37682-29-4
- MF:C14H21NO3
- Structure:
- Chemical Name:1-(2-Pyrimidyl)piperazine hydrochloride
- CAS:78069-54-2
- MF:C8H13ClN4
- Structure:
- Chemical Name:2-FLUOROTHIOANISOLE
- CAS:655-20-9
- MF:C7H7FS
- Structure:
- Chemical Name:m-Tolyldiethanolamine
- CAS:91-99-6
- MF:C11H17NO2
- Structure:
- Chemical Name:2-PHENOXYBENZOIC ACID
- CAS:2243-42-7
- MF:C13H10O3
- Structure:
- Chemical Name:Ethyl 4,4,4-trifluorobutyrate
- CAS:371-26-6
- MF:C6H9F3O2
- Structure:
- Chemical Name:ETHYL ISOPROPYL SULFONE
- CAS:4853-75-2
- MF:C5H12O2S
- Structure:
- Chemical Name:BIS(DIMETHYLAMINO)METHYLSILANE
- CAS:22705-33-5
- MF:C5H16N2Si
- Structure:
- Chemical Name:TETRABROMOPHENOLPHTHALEIN ETHYL ESTER
- CAS:1176-74-5
- MF:C22H14Br4O4
- Structure:
- Chemical Name:2-CHLOROETHYL PHENYL SULFIDE
- CAS:5535-49-9
- MF:C8H9ClS
- Structure:
- Chemical Name:Ethyl pivaloylacetate
- CAS:17094-34-7
- MF:C9H16O3
- Structure:
- Chemical Name:2-Benzyloxybenzaldehyde
- CAS:5896-17-3
- MF:C14H12O2
- Structure:
- Chemical Name:1,2-DIHYDRONAPHTHALENE
- CAS:447-53-0
- MF:C10H10
- Structure:
- Chemical Name:2-(Trifluoromethyl)cinnamic acid
- CAS:2062-25-1
- MF:C10H7F3O2
- Structure:
- Chemical Name:2-Bromo-1-indanone
- CAS:1775-27-5
- MF:C9H7BrO
- Structure:
- Chemical Name:5-BROMOPENTYL ACETATE
- CAS:15848-22-3
- MF:C7H13BrO2
- Structure:
- Chemical Name:Dichloromethylvinylsilane
- CAS:124-70-9
- MF:C3H6Cl2Si
- Structure:
- Chemical Name:Roxarsone
- CAS:121-19-7
- MF:C6H6AsNO6
- Structure:
- Chemical Name:ALPHA-METHYL-GAMMA-BUTYROLACTONE
- CAS:1679-47-6
- MF:C5H8O2
- Structure:
- Chemical Name:2,4,4-TRIMETHYL-2-PENTANETHIOL
- CAS:141-59-3
- MF:C8H18S
- Structure:
- Chemical Name:P-TOLUENETHIOSULFONIC ACID POTASSIUM SALT
- CAS:28519-50-8
- MF:C7H7KO2S2
- Structure:
- Chemical Name:METHYL HEPTADECANOATE
- CAS:1731-92-6
- MF:C18H36O2
- Structure:
- Chemical Name:3,4'-Dichloropropiophenone
- CAS:3946-29-0
- MF:C9H8Cl2O
- Structure:
- Chemical Name:Ethylene glycol diglycidyl ether
- CAS:2224-15-9
- MF:C8H14O4
- Structure:
- Chemical Name:N-Butylphthalimide
- CAS:1515-72-6
- MF:C12H13NO2
- Structure:
- Chemical Name:2,3,4-Trimethoxyphenylboronic acid
- CAS:118062-05-8
- MF:C9H13BO5
- Structure:
- Chemical Name:TRANS-STILBENE
- CAS:103-30-0
- MF:C14H12
- Structure:
- Chemical Name:Ethyl trifluoromethanesulfonate
- CAS:425-75-2
- MF:C3H5F3O3S
- Structure:
- Chemical Name:Diethyl butylmalonate
- CAS:133-08-4
- MF:C11H20O4
- Structure:
- Chemical Name:(1S)-1-(2-CHLOROPHENYL)ETHANE-1,2-DIOL
- CAS:133082-13-0
- MF:C8H9ClO2
- Structure:
- Chemical Name:METHYL 4-(BROMOMETHYL)-3-METHOXYBENZOATE
- CAS:70264-94-7
- MF:C10H11BrO3
- Structure:
- Chemical Name:N-Cyanoethyl-hydroxyethyl aniline
- CAS:92-64-8
- MF:C11H14N2O
- Structure:
- Chemical Name:(+)-DIPIVALOYL-D-TARTARIC ACID
- CAS:76769-55-6
- MF:C14H22O8
- Structure:
- Chemical Name:2,2-Diethoxyethanol
- CAS:621-63-6
- MF:C6H14O3
- Structure:
- Chemical Name:2,4,6-TRIHYDROXYBENZOIC ACID MONOHYDRATE
- CAS:71989-93-0
- MF:C7H8O6
- Structure:
- Chemical Name:3-Methoxy-2-nitrobenzaldehyde
- CAS:53055-05-3
- MF:C8H7NO4
- Structure:
- Chemical Name:3-Ethoxy-1-propanol
- CAS:111-35-3
- MF:C5H12O2
- Structure:
- Chemical Name:4-Chloro-1,3-benzenediamine
- CAS:5131-60-2
- MF:C6H7ClN2
- Structure:
- Chemical Name:1-CYCLOHEXYL-3-PHENYL-2-THIOUREA
- CAS:722-03-2
- MF:C13H18N2S
- Structure:
- Chemical Name:Dibenz[a,h]anthracene
- CAS:53-70-3
- MF:C22H14
- Structure:
- Chemical Name:4-Hexyloxyphenol
- CAS:18979-55-0
- MF:C12H18O2
- Structure:
- Chemical Name:S-PHENYL THIOACETATE
- CAS:934-87-2
- MF:C8H8OS
- Structure:
- Chemical Name:OCTANENITRILE
- CAS:124-12-9
- MF:C8H15N
- Structure:
- Chemical Name:Cyanomethyl benzenesulfonate
- CAS:10531-13-2
- MF:C8H7NO3S
- Structure:
- Chemical Name:Vinylmethyldimethoxysilane
- CAS:16753-62-1
- MF:C5H12O2Si
- Structure:
- Chemical Name:5,5'-Methylenedisalicylic acid
- CAS:122-25-8
- MF:C15H12O6
- Structure:
- Chemical Name:(R)-(-)-Methyl glycidyl ether
- CAS:64491-70-9
- MF:C4H8O2
- Structure:
- Chemical Name:1-(3,4-METHYLENEDIOXYPHENYL)-2-THIOUREA
- CAS:65069-55-8
- MF:C8H8N2O2S
- Structure:
- Chemical Name:1-Hexyl-3-methylimidazolium hexafluorophosphate
- CAS:304680-35-1
- MF:C10H19F6N2P
- Structure:
- Chemical Name:GAMMA-TERPINENE
- CAS:99-85-4
- MF:C10H16
- Structure:
- Chemical Name:Sodium dehydroacetate
- CAS:4418-26-2
- MF:C8H7NaO4
- Structure:
- Chemical Name:2-Iodoethanol
- CAS:624-76-0
- MF:C2H5IO
- Structure:
- Chemical Name:1-(3-CHLORO-2-METHYLPHENYL)-2-THIOUREA
- CAS:63980-70-1
- MF:C8H9ClN2S
- Structure:
- Chemical Name:4-FLUORO-3-NITROBENZALDEHYDE
- CAS:42564-51-2
- MF:C7H4FNO3
- Structure:
- Chemical Name:Dimethyl 2,2'-azobis(2-methylpropionate)
- CAS:2589-57-3
- MF:C10H18N2O4
- Structure:
- Chemical Name:3-(Chloromethyl)benzoyl chloride
- CAS:63024-77-1
- MF:C8H6Cl2O
- Structure:
- Chemical Name:3,4-Dimethylbenzophenone
- CAS:2571-39-3
- MF:C15H14O
- Structure:
- Chemical Name:1-Adamantanecarbonitrile
- CAS:23074-42-2
- MF:C11H15N
- Structure:
- Chemical Name:6,10-DIMETHYL-2,6,10,14-TETRAAZAPENTADECANE
- CAS:123-67-1
- MF:C13H32N4
- Structure:
- Chemical Name:Dodecyl isocyanate
- CAS:4202-38-4
- MF:C13H25NO
- Structure:
- Chemical Name:4-METHOXY-3-BUTEN-2-ONE
- CAS:4652-27-1
- MF:C5H8O2
- Structure:
- Chemical Name:1,2-CYCLOHEXANEDIONE DIOXIME
- CAS:492-99-9
- MF:C6H10N2O2
- Structure:
- Chemical Name:GUANYLUREA SULFATE
- CAS:591-01-5
- MF:C2H8N4O5S
- Structure:
- Chemical Name:PENTAERYTHRITYL TETRACHLORIDE
- CAS:3228-99-7
- MF:C5H8Cl4
- Structure:
- Chemical Name:2-DIPHENYLACETYL-1,3-INDANDIONE-1-HYDRAZONE
- CAS:5102-79-4
- MF:C23H18N2O2
- Structure:
- Chemical Name:Benzothiophene-3-boronic acid
- CAS:113893-08-6
- MF:C8H7BO2S
- Structure:
- Chemical Name:2-QUINOLINYLMETHANOL
- CAS:1780-17-2
- MF:C10H9NO
- Structure:
- Chemical Name:3,4,5-Trimethoxyphenol
- CAS:642-71-7
- MF:C9H12O4
- Structure:
- Chemical Name:Methyl 4-(chloroformyl)butyrate
- CAS:1501-26-4
- MF:C6H9ClO3
- Structure:
- Chemical Name:3,4-DICHLOROBENZYL MERCAPTAN
- CAS:36480-40-7
- MF:C7H6Cl2S
- Structure:
- Chemical Name:Dinonyl phthalate
- CAS:84-76-4
- MF:C26H42O4
- Structure:
- Chemical Name:METHYL 2-BUTYNOATE
- CAS:23326-27-4
- MF:C5H6O2
- Structure:
- Chemical Name:2-METHOXYETHYL P-TOLUENESULFONATE
- CAS:17178-10-8
- MF:C10H14O4S
- Structure:
- Chemical Name:1,3-DIMETHYLNAPHTHALENE
- CAS:575-41-7
- MF:C12H12
- Structure:
- Chemical Name:2-Phenoxypropionic acid
- CAS:940-31-8
- MF:C9H10O3
- Structure:
- Chemical Name:Ammonium benzenesulfonate
- CAS:19402-64-3
- MF:C6H9NO3S
- Structure:
- Chemical Name:BROMOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
- CAS:42014-51-7
- MF:C6H6BrNO4
- Structure:
- Chemical Name:2-Fluoro-6-methoxybenzaldehyde
- CAS:146137-74-8
- MF:C8H7FO2
- Structure:
- Chemical Name:4-N-HEPTYLOXYBENZOIC ACID
- CAS:15872-42-1
- MF:C14H20O3
- Structure:
- Chemical Name:ETHYL METHANESULFONYLACETATE
- CAS:4455-15-6
- MF:C5H10O4S
- Structure:
- Chemical Name:1-(4-METHOXYBENZYL)-2-THIOUREA
- CAS:37412-64-9
- MF:C9H12N2OS
- Structure:
- Chemical Name:5-Chloro-2-methylphenol
- CAS:5306-98-9
- MF:C7H7ClO
- Structure:
- Chemical Name:Biphenyl dimethyl dicarboxylate
- CAS:792-74-5
- MF:C16H14O4
- Structure:
- Chemical Name:(2-Methoxyphenyl)thiourea
- CAS:1516-37-6
- MF:C8H10N2OS
- Structure:
- Chemical Name:Benzamidine hydrochloride hydrate
- CAS:206752-36-5
- MF:C7H11ClN2O
- Structure:
- Chemical Name:3-Hydroxy-4-methoxyphenylacetic acid
- CAS:1131-94-8
- MF:C9H10O4
- Structure:
- Chemical Name:2-CYANOETHYLTRIETHOXYSILANE
- CAS:919-31-3
- MF:C9H19NO3Si
- Structure:
- Chemical Name:N-(2,4,6-TRIMETHYLPHENYL)THIOUREA
- CAS:91059-97-1
- MF:C10H14N2S
- Structure:
- Chemical Name:3-Ethoxysalicylaldehyde
- CAS:492-88-6
- MF:C9H10O3
- Structure:
- Chemical Name:p-Acetotoluidide
- CAS:103-89-9
- MF:C9H11NO
- Structure:
- Chemical Name:1,12-BENZOPERYLENE
- CAS:191-24-2
- MF:C22H12
- Structure:
- Chemical Name:1,1,3-Triphenylpropargyl alcohol
- CAS:1522-13-0
- MF:C21H16O
- Structure:
- Chemical Name:TETRAETHYLENEGLYCOL MONOMETHYL ETHER
- CAS:23783-42-8
- MF:C9H20O5
- Structure:
- Chemical Name:ETHYL PHENYLCYANOACETATE
- CAS:4553-07-5
- MF:C11H11NO2
- Structure:
- Chemical Name:4-Isopropoxyaniline
- CAS:7664-66-6
- MF:C9H13NO
- Structure:
- Chemical Name:2,6-Dibromo-4-methylphenol
- CAS:2432-14-6
- MF:C7H6Br2O