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ABT-263
ABT-263
$26 - $2245.7
Product name
ABT-263
Cas No
923564-51-6
MF
C47H55ClF3N5O6S3
MW
974.61
MDL Number
MFCD12756219
Synonyms
4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide;ABT 263;BenzaMide, 4-(4-((2-(4-chlorophenyl)-5,5-diMe;Benzamide, 4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((4-(((1R)-3-(4-morpholinyl)-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)-;ABT-263,Navitoclax;(S)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide;4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide ABT-26;ABT 263 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
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Cayman Chemical
Arctom
Chemenu
Crysdot
TRC
Biorbyt Ltd
ApexBio Technology
Matrix Scientific
AK Scientific
Medical Isotopes, Inc.
American Custom Chemicals Corporation
Biosynth Carbosynth
DC Chemicals
Package
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1unit
10mm(in1mldmso)
1mg
5mg
10mg
25mg
50mg
100mg
250mg
500mg
1g
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Brand
Packaging
Price
Product name
AK Scientific
SYN5340
10mg
$188
ABT-263
AK Scientific
X7535
100mg
$787
ABT-263
American Custom Chemicals Corporation
INB0009786
1MG
$452
ABT-263
American Custom Chemicals Corporation
INB0009786
5MG
$816.75
ABT-263
American Custom Chemicals Corporation
INB0009786
50MG
$2194.5
ABT-263
ApexBio Technology
A3007
100mg
$350
ABT-263(Navitoclax)
ApexBio Technology
A3007
50mg
$200
ABT-263(Navitoclax)
ApexBio Technology
A3007
1unit
$28
ABT-263(Navitoclax)
ApexBio Technology
A3007
5mg
$50
ABT-263(Navitoclax)
ApexBio Technology
A3007
10mg
$70
ABT-263(Navitoclax)
1
of
4
Properties
Melting point
114-116°C
Density
1.41±0.1 g/cm3(Predicted)
storage temp.
-20°C Freezer, Under Inert Atmosphere
solubility
Soluble in DMSO (up to 25 mg/ml).
form
solid
pka
4.60±0.10(Predicted)
color
White
Stability
Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey
JLYAXFNOILIKPP-KXQOOQHDSA-N
SMILES
C(NS(C1=CC=C(N[C@@H](CSC2=CC=CC=C2)CCN2CCOCC2)C(S(C(F)(F)F)(=O)=O)=C1)(=O)=O)(=O)C1=CC=C(N2CCN(CC3CC(C)(C)CCC=3C3=CC=C(Cl)C=C3)CC2)C=C1
CAS DataBase Reference
923564-51-6
Description
ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤1 nM in cell-free assays, but binds more weakly to Mcl-1 and A1. Phase 2.
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Suppliers and manufacturers
career henan chemical co
$2.00
/1KG
ABT 263
CAS:923564-51-6
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Henan Tianfu Chemical Co.,Ltd.
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Jinan Carbotang Biotech Co.,Ltd.
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