6-(ブロモメチル)-2,4-プテリジンジアミン臭化水素酸塩

危険有害性情報のコード(GHS)

• 絵表示(GHS)

  

• 注意喚起語

  Warning

• 危険有害性情報

  H302：飲み込むと有害

  H315：皮膚刺激

  H319：強い眼刺激

  H335：呼吸器への刺激のおそれ

• 注意書き

  P261：粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。

  P305+P351+P338：眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

6-(ブロモメチル)-2,4-プテリジンジアミン臭化水素酸塩 価格

6-(ブロモメチル)-2,4-プテリジンジアミン臭化水素酸塩 化学特性,用途語,生産方法

• 説明

  6-(Bromomethyl)-2,4-pteridinediamine hydrobromide is a potent inhibitor of the enzyme nitroaldolase (EC 1.2.1.22) and has been shown to inhibit cell growth in murine leukemia cells. This reaction is mediated by the addition of bromide to isobutyl esters, leading to a benzyl ester intermediate which undergoes an electrophilic attack on nitroaldolase. The mechanism of action for this drug involves the inhibition of membrane transport and chloride ion influx, which are necessary for the proliferation of tumor cells. 6-(Bromomethyl)-2,4-pteridinediamine hydrobromide also inhibits DNA synthesis through its effects on thymidylate synthase, preventing nucleotide production from thymine and dihydrofolate reductase activity.

• 化学的特性

  Light Brown Solid

• 使用

  6-(Bromomethyl)-2,4-pteridinediamine hydrobromide can be used as organic synthesis intermediate and pharmaceutical intermediate.

• 主な応用

  6-(Bromomethyl)-2,4-pteridinediamine Hydrobromide (Technical Grade) is a useful research chemical used in the preparation of novel methotrexate derivatives as antirheumatic agents as well as the preparation of pteridine reductase inhibitors.

6-(ブロモメチル)-2,4-プテリジンジアミン臭化水素酸塩 上流と下流の製品情報

6-(ブロモメチル)-2,4-プテリジンジアミン臭化水素酸塩 生産企業

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52853-40-4, 6-(ブロモメチル)-2,4-プテリジンジアミン臭化水素酸塩 キーワード