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LINDERANE

LINDERANE Structure
LINDERANE
  • CAS No.13476-25-0
  • Chemical Name:LINDERANE
  • CBNumber:CB9243408
  • Molecular Formula:C15H16O4
  • Formula Weight:260.29
  • MOL File:13476-25-0.mol
LINDERANE Property
  • Melting point 190～191℃
  • Boiling point 434.5±45.0 °C(Predicted)
  • Density 1.30±0.1 g/cm3(Predicted)
  • storage temp. -20°C
  • solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
  • form Solid
  • color White to Off-White
  • Stability Hygroscopic
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
  • Safety Statements  :24/25
  • HS Code  :29322090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

LINDERANE Chemical Properties,Usage,Production

  • Description Linderane is a sesquiterpene that has been found in L. aggregata. It inhibits the cytochrome P450 (CYP) isoform CYP2C9 (Ki = 1.26 μM) in an irreversible and NADPH-dependent manner. Linderane decreases phosphoenolpyruvate carboxykinase (Pck1) and glucose-6-phosphatase (G6pc) gene expression, cAMP concentration, and CREB phosphorylation, increases phosphodiesterase 3 (PDE3) activity, and inhibits gluconeogenesis in rat primary hepatocytes. In vivo, linderane (50 mg/kg twice per day) decreases serum and hepatic triglyceride levels, as well as random-fed and fasting blood glucose levels in ob/ob mice.
  • Uses Linderane is a sequiterpene lactone extract from Lindera strychnifolia compound used as a cytotoxic agent against hepaic stellate cells.
  • Definition ChEBI: Linderane is a member of dioxanes.
  • IC 50 CYP2
LINDERANE Preparation Products And Raw materials
Raw materials
Preparation Products
LINDERANE Suppliers
Global(199)Suppliers
  • Supplier：
    Henan Tianfu Chemical Co.,Ltd.
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  • Supplier：
    career henan chemical co
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  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    Aktin Chemicals, Inc.
  • Tel：028-85159085
  • Email：info@aktinchem.com
  • Country：CHINA
  • ProdList：1025
  • Advantage：58
LINDERANE Spectrum
13476-25-0, LINDERANERelated Search:
  • pharmaceutical intermediate
  • chemical reagent
  • standardized herbal extract
  • reference standards from Chinese medicinal herbs (TCM).
  • phytochemical
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  • 中药标准品
  • 乌药醚内酯/HPLC
  • 标准品对照品】LINDERANE
  • 乌药醚内酯(对照品)
  • 乌药环氧内酯
  • 乌药迷内脂
  • 乌药醚内酯LINDERANE
  • LINDERANE 乌药醚内酯 标准品
  • 乌药谜內脂, 来源于乌药
  • 乌药醚内酯 20MG
  • LINDERANE 乌药醚内酯
  • 乌药醚内酯(标准品)
  • 乌药谜內脂
  • 乌药醚内脂
  • 乌药醚内酯
  • 13476-25-0
  • Linderane-RM
  • linerane
  • wuyaomineizhi
  • Linderane, 98%, from Lindera aggregata (Sims) Kosterm.
  • Linderane ,98%
  • LINDERANE(RG)
  • (1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-2H-10,1a-(epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one
  • (1aS,4E,10S,10aS)-3,6,10,10a-Tetrahydro-5,9-dimethyl-10,1a-(epoxymethano)-2H-oxireno[4,5]cyclodeca[1,2-b]furan-12-one
  • 2H-10,1a-(Epoxymethano)oxireno[4,5]cyclodeca[1,2-b]furan-12-one,3,6,10,10a-tetrahydro-5,9-dimethyl-, (1aS,4E,10S,10aS)-
  • LINDERANE

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