Description
A steroidal alkaloid isolated from the bulbs of Fritillaria irnperialis L. and
Petiliurn eduardi, the base crystallizes in short, colourless needles and has
[α]
D - 35.4° (CHCI3). It yields crystalline salts and with sucrose gives a
sequence of characteristic colours on addition of dilute H2S04 from yellowgreen, through pale green, pink, cherry red, to dark violet. The structure has been
determined from mass spectrometry and the NMR spectrum, the latter proving
the presence of tertiary hydroxyl and methyl groups at C-20.
Chemical Properties
White needle-like crystals, easily soluble in chloroform, ethyl acetate, soluble in methanol, ethanol, acetone, ethyl ether, insoluble in water and petroleum ether, from Chuanbeimu.
Occurrence
A steroidal alkaloid, kashmirine has been obtained from Fritillaria raylei. It furnishes
colourless needles when crystallized from EtOH and is laevorotatory with a specific rotation
of [α]D -40.4° (CHCI3).
Uses
Imperialine is an isosteroidal alkaloid from Fritillaria thunbergii.
Definition
ChEBI: Sipeimine is an alkaloid.
References
Fragner., Ber., 28,3284 (1888)
Structure:
Nuriddinov, Shakirov, Yunusov., Khirn. Prir. Soedin., 3,316 (1967)
