ChemicalBook > CAS DataBase List > Azido-PEG11-azide
Azido-PEG11-azide
Azido-PEG11-azide
- CAS No.1392284-57-9
- Chemical Name:Azido-PEG11-azide
- CBNumber:CB83049415
- Molecular Formula:C24H48N6O11
- Formula Weight:596.68
- MOL File:1392284-57-9.mol
Azido-PEG11-azide Property
- form Liquid
- color Colorless to light yellow
- Symbol(GHS)
- Signal word
- Hazard statements
- Precautionary statements
Azido-PEG11-azide Chemical Properties,Usage,Production
- Description Azido-PEG11-azide is a aqueous soluble, monodisperse PEG linker containing two azide groups.The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
- Uses Azido-PEG11-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG11-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- IC 50 PEGs
- References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG11-azide Preparation Products And Raw materials
Raw materials
Preparation Products
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1392284-57-9, Azido-PEG11-azideRelated Search:
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- CAS_1392284-57-9
- Azido-PEG11-azide