ChemicalBook > CAS DataBase List > N3-PEG3-tBu

N3-PEG3-tBu

N3-PEG3-tBu Structure
N3-PEG3-tBu
  • CAS No.252881-73-5
  • Chemical Name:N3-PEG3-tBu
  • CBNumber:CB12546985
  • Molecular Formula:C13H25N3O5
  • Formula Weight:303.3547
  • MOL File:252881-73-5.mol
N3-PEG3-tBu Property
  • form Liquid
  • color Colorless to light yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

N3-PEG3-tBu Chemical Properties,Usage,Production

  • Description Azido-PEG3-t-butyl ester is a click chemistry reagent. The hydrophilic PEG spacer increases solubility in aqueous media. The azide (N3) group canis reactive with alkyne, such as BCN, DBCO via Click Chemistry. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
  • Uses Azido-PEG3-t-butyl Ester is used as a linker in the conjugation of peptides.
  • Biological Activity N3-PEG3-tBu is a cleavable ADC linker containing 3-unit PEG, which can be used to synthesize antibody drug conjugates (ADC). It is also a PROTAC linker, belonging to the PEG and Alkyl/ether classes, which can be used to synthesize PROTAC molecules.
  • in vitro

    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

  • target

    PEGs

    Alkyl/ether

    Cleavable

N3-PEG3-tBu Preparation Products And Raw materials
Raw materials
Preparation Products
Global(99)Suppliers
  • Supplier:
    9i LLC
  • Tel:+18039569191
  • Email:MWan@NiNeiLab.com
  • Country:United States
  • ProdList:418
  • Advantage:58
  • Supplier:
    TargetMol Chemicals Inc.
  • Tel:+1-781-999-5354<br/>+1-00000000000
  • Email:marketing@targetmol.com
  • Country:United States
  • ProdList:32159
  • Advantage:58
  • Supplier:
    Wuhan Borenpharm Co., Ltd
  • Tel:027-65563561<br/>18717150066
  • Email:3207347307@qq.com
  • Country:CHINA
  • ProdList:1238
  • Advantage:58
  • Supplier:
    Nextpeptide Inc
  • Tel:+86-0571-81612335<br/>+8613336028439
  • Email:sales@nextpeptide.com
  • Country:China
  • ProdList:19908
  • Advantage:58
  • Supplier:
    LEAPCHEM CO., LTD.
  • Tel:+86-852-30606658
  • Email:market18@leapchem.com
  • Country:China
  • ProdList:43340
  • Advantage:58
N3-PEG3-tBu Spectrum
252881-73-5, N3-PEG3-tBuRelated Search:
  • peg
  • SiChem
  • 抑制剂
  • PEG系列产品-N3-PEG系列
  • 药靶配体
  • 聚乙二醇修饰剂
  • 叠氮-PEG3-TBU酯
  • 化合物 N3-PEG3-CH2CH2-BOC
  • 3-(2-(2-(2-叠氮乙氧基)乙氧基)乙氧基)丙酸叔丁酯
  • 叠氮三聚乙二醇缬氨酸叔丁酯
  • 叠氮-三聚乙二醇-叔丁酯
  • 3-[2-[2-(2-叠氮基乙氧基)乙氧基]乙氧基]丙酸叔丁酯
  • 叠氮-三乙二醇-丙酸叔丁酯
  • 3-[2-[2-(2-叠氮基乙氧基)乙氧基]乙氧基]丙酸叔丁酯
  • 3-[2-[2-(2-叠氮基乙氧基)乙氧基]乙氧基]丙酸叔丁酯 1G
  • 252881-73-5
  • N3-PEG3-CH2CH2COO<SUP>t<
  • Azido-PEG3-CH2CH2COOtBu
  • N3-PEG3-CH2CH2COOtBu/Propanoic acid, 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
  • Azido-PEG3-tBu Ester
  • N3-(CH2CH2O)3-CH2CH2COOt-Bu
  • N?-PEG?-CH?CH?COOtBu
  • N3-PEG3-CH2CH2-Boc
  • N3-?PEG3-?t-?butyl ester
  • tert-Butyl 3-(2-(2-(2-azidoethoxyl)ethoxy)ethoxy)propanoate
  • Azido-PEG3-COOtBu
  • tert-butyl 3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)propanoate
  • 3-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]propanoic acid 1,1-dimethylethyl ester
  • N3-PEG3-CH2CH2COOtBu
  • N3-PEG3-tBu
  • N<SUB>3</SUB>-PEG<SUB>3</SUB>-CH<SUB>2</SUB>CH<SUB>2</SUB>COO<SUP>t</SUP>Bu