ChemicalBook > CAS DataBase List > H2N-PEG6-tBu

H2N-PEG6-tBu

H2N-PEG6-tBu Property

Boiling point 475.9±40.0 °C(Predicted)
Density 1.056±0.06 g/cm3(Predicted)
refractive index n/D 1.4562
storage temp. -20°C
form Oil
pka 8.74±0.10(Predicted)
color Colorless to light yellow
InChI InChI=1S/C19H39NO8/c1-19(2,3)28-18(21)4-6-22-8-10-24-12-14-26-16-17-27-15-13-25-11-9-23-7-5-20/h4-17,20H2,1-3H3
InChIKey QGSFECNPSLZGGT-UHFFFAOYSA-N
SMILES C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCOCCN
UNSPSC Code 51171641
NACRES NA.22

Safety

Hazard and Precautionary Statements (GHS)

H2N-PEG6-tBu Price More Price(2)

H2N-PEG6-tBu Chemical Properties,Usage,Production

Description Amino-PEG6-t-butyl ester is a PEG reagent containing an amino NH2 group with a t-butyl protected carboxyl group (Boc). The hydrophilic PEG spacer increases solubility in aqueous media. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses This heterobifunctional, PEGylated crosslinker features an amino group at one end and t-butyl-protected carboxyl group at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Amino-PEG6-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC^? molecules) for targeted protein degradation.
reaction suitability reagent type: cross-linking reagent
IC 50 PEGs; Alkyl/ether; Non-cleavable Linker

H2N-PEG6-tBu Preparation Products And Raw materials

Raw materials

Preparation Products

H2N-PEG6-tBu Suppliers

Global(117)Suppliers

H2N-PEG6-tBu Spectrum

1286281-32-0, H2N-PEG6-tBuRelated Search:

peg
PEGylated Carboxylate
抑制剂
PEG系列产品-NH2-PEG系列
高端化学
助剂
其它
基准试剂
C19H39NO8
氨基-PEG6-BU酯
氨基-PEG7-叔丁酯
氨基-七聚乙二醇-乙酸叔丁酯
氨基七聚乙二醇叔丁酯
1-氨基-3,6,9,12,15,18-六氧代苯甲酸-21-酸叔丁酯
AMINO-PEG6-T-BUTYLESTER,氨基-六聚乙二醇丙酸叔丁酯
氨基六聚乙二醇缬氨酸叔丁酯
胺基-七聚乙二醇-丙酸叔丁酯
胺基-六聚乙二醇-丙酸叔丁酯
氨基-PEG6-叔丁酯
氨基六聚乙二醇叔丁酯
氨基-六乙二醇-丙酸叔丁酯
氨基-五聚乙二醇-丙酸叔丁酯
氨基-六聚乙二醇-丙酸叔丁酯
1286281-32-0
Amino-dPEG??-t-butyl ester (QBD-10061)
tert-butyl 3-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
NH-2-PEG6-Boc,inhibit,ADC Linkers,Antibody-drug conjugates linkers,PROTAC Linkers,Inhibitor,NH2PEG6Boc,NH2 PEG6 Boc
H2N-PEG6-CH2CH2COOtBu/4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-amino-, 1,1-dimethylethyl ester
Amino-PEG6-t-Bu Ester
NH2-PEG6-C2-COOtBu
tert-Butyl 1-amino-3,6,9,12,15,18-hexaoxahenicosan-21-oate
H2N-PEG6-CH2CH2COOtBu
NH2-PEG7-CH2COOtBu
Amino-dPEG??-t-butyl ester
t-Butyl 3-Amino(peg6)propionate
4,7,10,13,16,19-Hexaoxaheneicosanoic acid, 21-amino-, 1,1-dimethylethyl ester
Amino-PEG6-t-butylester,H2N-PEG6-t-butyl ester
NH2-PEG6-Boc
H2N-PEG6-CH2CH2-t-butylester
Amino-PEG6-COOtBu
NH2-PEG6-CH2CH2COOtBu
Amino-PEG7-t-butyl ester
Amino-PEG6-t-butyl ester
H2N-PEG6-tBu