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HO-PEG5-tBu

HO-PEG5-tBu Structure
HO-PEG5-tBu
  • CAS No.850090-09-4
  • Chemical Name:HO-PEG5-tBu
  • CBNumber:CB12546899
  • Molecular Formula:C17H34O8
  • Formula Weight:366.45
  • MOL File:850090-09-4.mol
HO-PEG5-tBu Property
  • Boiling point 445.4±40.0 °C(Predicted)
  • Density 1.071
  • refractive index n/D 1.448
  • storage temp. -20°C
  • form liquid
  • pka 14.36±0.10(Predicted)
  • color Colorless to light yellow
  • UNSPSC Code 51171641
Safety
  • HS Code  :2918999090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P280-P305+P351+P338
HO-PEG5-tBu Price More Price(2)
  • Brand: Sigma-Aldrich(India)
  • Product number: 902691
  • Product name : Hydroxy-PEG5-t-butyl ester
  • Purity: 
  • Packaging: 250MG
  • Price: ₹27603.75
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: 902691
  • Product name : Hydroxy-PEG5-t-butyl ester
  • Purity: 
  • Packaging: 1G
  • Price: ₹81025.13
  • Updated: 2022/06/14
  • Buy: Buy

HO-PEG5-tBu Chemical Properties,Usage,Production

  • Description Hydroxy-PEG5-t-butyl ester is a PEG linker containing a hydroxyl group with a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
  • Uses This heterobifunctional, PEGylated crosslinker features a hydroxyl group at one end and t-butyl-protected carboxylic acid at the other, which can be deprotected with acidic conditions. The hydrophillic PEG linker facilitates solubility in biological applications. Hydroxy-PEG5-t-butyl ester can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC? molecules) for targeted protein degradation.
  • reaction suitability reagent type: cross-linking reagent
  • IC 50 PEGs
HO-PEG5-tBu Preparation Products And Raw materials
Raw materials
Preparation Products
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HO-PEG5-tBu Spectrum
850090-09-4, HO-PEG5-tBuRelated Search:
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  • tert-butyl 3-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]propanoate
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  • PROTAC Linkers,Inhibitor,Hydroxy-PEG-5-Boc,inhibit,HydroxyPEG5Boc,Hydroxy PEG5 Boc
  • HO-PEG5-COOtBu
  • tert-Butyl 1-hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oate
  • OH-PEG5-CH2CH2COOtBu
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  • HO-PEG?-CH?CH?COOtBu
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  • Hydroxy-PEG5-Boc
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  • Hydroxy-PEG5-t-butly ester
  • OH-PEG5-TBA
  • HO-PEG5-tBu
  • Hydroxy-PEG5-CH2CO2tBu
  • HO-PEG<sub>5</sub>-CH<sub>2</sub>CH<sub>2</sub>COO<sup>t</sup>Bu
  • 1-Hydroxy-3,6,9,12,15-pentaoxaoctadecan-18-oic acid 1,1-dimethylethyl ester