Description
Fmoc-NH-PEG3-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Chemical Properties
Fmoc-NH-PEG3-CH2COOH Appearance is colourless to light yellow viscous liquid, stored at -20℃.
Uses
Fmoc-9-amino-4,7-dioxanonanoic acid is an amino acid derivative and can be used as a pharmaceutical intermediate.
