ChemicalBook > CAS DataBase List > FMoc-NH-5(ethylene glycol)-acetic acid

FMoc-NH-5(ethylene glycol)-acetic acid

FMoc-NH-5(ethylene glycol)-acetic acid Structure
FMoc-NH-5(ethylene glycol)-acetic acid
  • CAS No.635287-26-2
  • Chemical Name:FMoc-NH-5(ethylene glycol)-acetic acid
  • CBNumber:CB42546850
  • Molecular Formula:C27H35NO9
  • Formula Weight:517.57
  • MOL File:635287-26-2.mol
FMoc-NH-5(ethylene glycol)-acetic acid Property
  • Boiling point 704.3±60.0 °C(Predicted)
  • Density 1.224±0.06 g/cm3(Predicted)
  • storage temp. 2-8°C
  • pka 3.39±0.10(Predicted)
  • form Viscous Liquid
  • color Colorless to light yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

FMoc-NH-5(ethylene glycol)-acetic acid Chemical Properties,Usage,Production

  • Description Fmoc-NH-PEG5-CH2COOH is a PEG linker containing an Fmoc-protected amine and a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
  • Biological Activity Fmoc-NH-PEG5-CH2COOH is a degradable ADC linker for antibody drug conjugate (ADC) synthesis. It is also a PEG-based PROTAC linker, which can be used for PROTAC synthesis.
  • in vitro

    ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
    PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

  • target

    Cleavable

    Alkyl/ether

    PEGs

FMoc-NH-5(ethylene glycol)-acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
FMoc-NH-5(ethylene glycol)-acetic acid Suppliers
Global(92)Suppliers
  • Supplier：
    9i LLC
  • Tel：+18039569191
  • Email：MWan@NiNeiLab.com
  • Country：United States
  • ProdList：418
  • Advantage：58
  • Supplier：
    Accela ChemBio Inc.
  • Tel：+1-858-6993322
  • Email：info@accelachem.com
  • Country：United States
  • ProdList：19825
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    Wuhan Borenpharm Co., Ltd
  • Tel：027-65563561<br/>18717150066
  • Email：3207347307@qq.com
  • Country：CHINA
  • ProdList：1238
  • Advantage：58
  • Supplier：
    Nextpeptide Inc
  • Tel：+86-0571-81612335<br/>+8613336028439
  • Email：sales@nextpeptide.com
  • Country：China
  • ProdList：19908
  • Advantage：58
  • Supplier：
    Labnetwork lnc.
  • Tel：+86-27-50766799<br/>+8618062016861
  • Email：contact@labnetwork.com
  • Country：China
  • ProdList：19987
  • Advantage：58
FMoc-NH-5(ethylene glycol)-acetic acid Spectrum
635287-26-2, FMoc-NH-5(ethylene glycol)-acetic acidRelated Search:
  • peg
  • 化学试剂
  • 抑制剂
  • PEG系列产品-Fmoc-PEG系列
  • 聚乙二醇衍生物-异官能团
  • 助剂
  • PEG类产品-Fmoc-PEG
  • 其它
  • 聚乙二醇修饰剂
  • 化合物 FMOC-NH-PEG5-CH2COOH
  • 芴甲氧羰基五聚乙二醇乙酸
  • FMOC-NH-5(ETHYLENE GLYCOL)-ACETIC ACID,98%
  • 芴甲氧羰基-PEG5-乙酸
  • 中文名称:5,8,11,14,17-五氧杂-2-氮杂十九烷二酸 1-芴甲基酯英文名称:FMOC-NH-PEG5-CH2COOH
  • FMOC-NH-5(乙二醇)-乙酸
  • 芴甲氧羰基五聚乙二醇羧甲基
  • FMOC酰胺-五聚乙二醇-乙酸
  • 芴甲氧羰氨基五聚乙二醇乙酸
  • N-芴甲氧羰基-五聚乙二醇-乙酸
  • 5,8,11,14,17-五氧杂-2-氮杂十九烷二酸 1-芴甲基酯
  • 635287-26-2
  • Fmoc-N-amido-PEG5-acetic acid
  • 2-[2-[2-[2-[2-[2-(9H-fluoren-9-ylmethoxycarbonylamino)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid
  • Fmoc-NH-PEG5-CH2COOH(1-(9H-Fluoren-9-ylmethyl) 5,8,11,14,17-pentaoxa-2-azanonadecanedioate)
  • FmocNH-PEG5-CH2COOH/5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester
  • FmocNH-P5-CH2CO2H
  • {2-[2-(2-{2-[2-(9H-fluoren-9-yl-methoxycarbonylamino)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}acetic acid
  • 17-[(9-Fluorenylmethoxycarbonyl)amino]-3,6,9,12,15-pentaoxaheptadecanoic acid
  • Fmoc-NH-5(ethylene glycol)-actic acid
  • 5,8,11,14,17-Pentaoxa-2-azanonadecanedioic acid 1-(9H-fluoren-9-ylmethyl) ester
  • FMoc-NH-PEG5-CH2COOH
  • FMoc-NH-5(ethylene glycol)-acetic acid
  • 1-(9H-Fluoren-9-yl)-3-oxo-2,7,10,13,16,19-hexaoxa-4-azahenicosan-21-oic acid
  • Fmoc-PEG5-acetic acid

Home

My