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Amino-PEG4-acid

Amino-PEG4-acid Structure
Amino-PEG4-acid
  • CAS No.663921-15-1
  • Chemical Name:Amino-PEG4-acid
  • CBNumber:CB92501434
  • Molecular Formula:C11H23NO6
  • Formula Weight:265.3
  • MOL File:663921-15-1.mol
Amino-PEG4-acid Property
  • Boiling point 409.6±40.0 °C(Predicted)
  • Density 1.134±0.06 g/cm3(Predicted)
  • storage temp. 2-8°C
  • pka 4.28±0.10(Predicted)
  • form powder
  • color White
  • InChI InChI=1S/C11H23NO6/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h1-10,12H2,(H,13,14)
  • InChIKey DKUZHSDZSMQOGQ-UHFFFAOYSA-N
  • SMILES C(O)(=O)CCOCCOCCOCCOCCN
  • UNSPSC Code 12352106
  • NACRES NA.22
Safety
  • HS Code  :2942000090
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302-H315-H319-H335
  • Precautionary statements P280-P301+P312-P261
Amino-PEG4-acid Price More Price(1)
  • Brand: Sigma-Aldrich(India)
  • Product number: QBD10244
  • Product name : Amino-dPEG®4-acid
  • Purity: >95% (HPLC)
  • Packaging: 100MG
  • Price: ₹11355.43
  • Updated: 2022/06/14
  • Buy: Buy

Amino-PEG4-acid Chemical Properties,Usage,Production

  • Description Amino-PEG4-acid is a very popular PEG linker. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond, long PEG spacer increases reagent's solubility in aqueous media.
  • Uses H2N-Dpeg(4)-COOH, can be used in optical imaging of integrin αvβ3 expression with near-infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers. Integrin αvβ3 plays great roles in tumor angiogenesis, invasion, and metastasis.
  • benefits Amino-dPEG4-acid has a primary amine and propionic acid terminating opposite ends of a 16-atoms long (18.0 ?) polyethylene glycol (PEG) spacer. The single molecular weight PEG spacer is discrete (D = 1). Moreover, it is highly hydrophilic, and it imparts hydrophilicity to conjugates that incorporate it. Amino-dPEG4-acid is useful in many different applications, including peptide synthesis, surface modification, dendrimer construction, and small molecule modification.
  • reaction suitability reaction type: Pegylations
  • IC 50 Cleavable Linker; PEGs
  • References 1. Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers. DOI:10.1021/mp800150r
    2. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. DOI:10.1021/bc400050k
    3. Microwave-mediated synthesis of labeled nucleotides with utility in the synthesis of DNA probes. DOI:10.1021/bc100013b
    4. Improving tumor uptake and pharmacokinetics of (64)Cu-labeled cyclic RGD peptide dimers with Gly(3) and PEG(4) linkers. DOI:10.1021/bc800455p
Amino-PEG4-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Amino-PEG4-acid Suppliers
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Amino-PEG4-acid Spectrum
663921-15-1, Amino-PEG4-acidRelated Search:
  • peg
  • PEG-COOH
  • 抑制剂
  • PEG系列产品-NH2-PEG系列
  • 药靶配体
  • 助剂
  • PEG类产品
  • 其它
  • 基准试剂
  • 聚乙二醇修饰剂
  • C11H23NO6
  • 3-[2-[2-[2-(2-氨基乙氧基)乙氧基]乙氧基]乙氧基]丙酸/663921-15-1
  • 伪-AMINE-蠅-PROPIONIC ACID TETRAETHYLENE GLYCOL
  • 氨基聚乙二醇4羧基
  • 氨基-PEG4-羧酸
  • 3-[2-[2-[2-(2-氨基乙氧基)乙氧基]乙氧基]乙氧基]丙酸盐酸盐
  • Α-胺-Ω-丙酸四甘醇
  • 1-氨基-3,6,9,12-四氧代十五烷-15-酸盐酸盐
  • 氨基四聚乙二醇丙酸
  • AMINO-PEG4-ACID,NH2-PEG4-COOH
  • 氨基四聚乙二醇羧乙基
  • 3-[2-[2-[2-(2-氨基乙氧基)乙氧基]乙氧基]乙氧基]丙酸
  • 胺基-四聚乙二醇-丙酸
  • 1-氨基-3,6,9,12-四氧杂-15-十五烷酸
  • 1-氨基-3,6,9,12-四氧代十五烷-15-酸
  • 3-[2-[2-[2-(2-氨基乙氧基)乙氧基]乙氧基]乙氧基]丙酸
  • 1-氨基-3,6,9,12-四氧杂十五烷-15-酸
  • 氨基-四聚乙二醇-羧酸
  • 3-[2-[2-[2-(2-氨基乙氧基)乙氧基]乙氧基]乙氧基]丙酸 1G
  • 氨基-四乙二醇-羧酸
  • 663921-15-1
  • Amino-dPEG??-acid (QBD-10244)
  • NH2-PEG4-PA
  • H2N-PEG4-CH2CH2COOH/Propanoic acid, 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-
  • NH2-PEG4-CH2CH2COOH
  • NH2-PEG4-COOH
  • Amino-PEG4-acid
  • 1-AMino-3,6,9,12-tetraoxapentadecan-15-oic acid
  • 3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionic acid
  • α-Amine-ω-propionic acid tetraethylene glycol hydrochloride
  • 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
  • Propanoic acid, 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-
  • α-Amine-ω-propionic acid tetraethylene glycol,Amino-PEG4-acid
  • 1-Amino-3,6,9,12-tetraoxa-15-pentadecanoic Acid
  • 3-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]propanoic acid
  • 3-Amino(peg4)propionic acid
  • Amino-PEG4-COOH
  • AMINE-PEG4-COOH
  • Amino-PEG4-propionic acid
  • amino-dPEG4-acid
  • Amino-dPEGx-acid
  • H2N-PEG4-CH2CH2COOH
  • alpha-aMine-oMega-propionic acid tetraethylene glycol
  • α-amine-ω-propionic acid tetraethylene glycol

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