ChemicalBook > CAS DataBase List > alpha, oMega-Dipropionic acid hexaethylene glycol
alpha, oMega-Dipropionic acid hexaethylene glycol
- CAS No.94376-75-7
- Chemical Name:alpha, oMega-Dipropionic acid hexaethylene glycol
- CBNumber:CB02546887
- Molecular Formula:C18H34O11
- Formula Weight:426.46
- MOL File:94376-75-7.mol
alpha, oMega-Dipropionic acid hexaethylene glycol Property
- form Viscous Liquid
- color Colorless to light yellow
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H335
- Precautionary statements P261-P305+P351+P338
alpha, oMega-Dipropionic acid hexaethylene glycol Chemical Properties,Usage,Production
- Description Bis-PEG7-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
- Uses Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
- Biological Activity Bis-PEG7-acid is a PROTAC linker belonging to the PEG class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
-
target
PEGs
Cleavable
- IC 50 PEGs; Cleavable Linker
- References [1] Marc Stefan ROBILLARD, et al. Tetrazines for high click conjugation yield in vivo and high click release yield. WO2019212356A1
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- peg
- PEG系列产品-Bis-PEG系列
- 助剂
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- 94376-75-7
- COOHCH2CH2-PEG6-CH2CH2COOH
- 3-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
- HOOCCH2CH2O-PEG6-CH2CH2COOH/4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid
- Di-Acid-PEG7
- Bis(3-PEG6)propionic acid
- Bis-PEG7-COOH
- 3-(2-{2-[2-(2-{2-[2-(2-Carboxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}-ethoxy)propionic acid
- HOOCCH2CH2O-PEG6-CH2CH2COOH
- Bis-PEG8-acid
- COOH-PEG7-COOH
- COOH-PEG6-COOH
- Bis-PEG7-acid
- 4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid
- α,ω-Dipropionic acid hexaethylene glycol
- HOOC-PEG6-COOH
- alpha, oMega-Dipropionic acid hexaethylene glycol
