ChemicalBook > CAS DataBase List > Bis-PEG10-acid
Bis-PEG10-acid
- CAS No.1268488-70-5
- Chemical Name:Bis-PEG10-acid
- CBNumber:CB02747165
- Molecular Formula:C22H42O13
- Formula Weight:514.56
- MOL File:1268488-70-5.mol
Bis-PEG10-acid Property
- Boiling point 630.0±55.0 °C(Predicted)
- Density 1.174±0.06 g/cm3(Predicted)
- storage temp. 2-8°C
- pka 3.97±0.10(Predicted)
- form Solid
- color White to off-white
-
Symbol(GHS)
- Signal wordWarning
- Hazard statements H302-H315-H319-H335
- Precautionary statements P261-P280-P301+P312-P302+P352-P305+P351+P338
Bis-PEG10-acid Chemical Properties,Usage,Production
- Description Bis-PEG9-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
- Uses Bis-??PEG9-??acid is used in the preparation of plasma-stable dimeric inhibitors of PSD-95-NMDA receptor interaction.
- Biological Activity Bis-PEG10-acid is a PROTAC linker belonging to the PEG class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
-
target
PEGs
Cleavable
- IC 50 PEGs; Cleavable Linker
Bis-PEG10-acid Preparation Products And Raw materialsRaw materialsPreparation ProductsGlobal(75)Suppliers-
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1268488-70-5, Bis-PEG10-acidRelated Search:- HOOC-PEG7-CH2CH2COOH alpha, oMega-Dipropionic acid triethylene glycol α,ω-dipropionic acid tetraethylene glycol Bis-PEG2-acid Bis-PEG6-acid α,ω,-dipropionic acid nonaethylene glycol Bis-PEG9-t-butyl ester Bis-PEG9-acid Bis-PEG4-acid Bis-PEG11-t-butyl ester Bis-PEG6-t-butyl ester Bis-PEG5-t-butyl ester alpha-(2-Carboxyethyl)-omega-(2-carboxyethoxy)poly(oxy-1,2-ethanediyl) Bis-PEG4-t-butyl ester alpha, oMega-Dipropionic acid hexaethylene glycol HOOC-PEG10-COOH alpha, oMega-Dipropionic acid nonaethylene glycol HOOC-PEG24-COOH
- peg
- PROTAC
- PROTAC Linker
- 抑制剂
- PEG系列产品-Bis-PEG系列
- 助剂
- C54H106O29
- C46H90O25
- C22H42O13
- 化合物 BIS-PEG9-ACID
- 羧基聚乙二醇8羧基
- 双羧基聚乙二醇
- 丙酸-九聚乙二醇-丙酸
- 羧酸-PEG9-羧酸
- 4,7,10,13,16,19,22,25,28-九氧杂三十一烷-1,31-二酸
- 4,7,10,13,16,19,22,25,28-壬恶烷二乙酸
- 羧基八聚乙二醇羧乙基
- 双羧基九聚乙二醇
- 羧酸-八聚乙二醇-羧酸
- 1268488-70-5
- alpha,omega-Bis(propionic acid) 20(ethylene glycol)
- COOHCH2CH2-PEG8-CH2CH2COOH
- HOOCCH2CH2O-PEG8-CH2CH2COOH/4,7,10,13,16,19,22,25,28-Nonaoxahentriacontanedioic acid
- Di-Acid-PEG9
- 4,7,10,13,16,19,22,25,28-Nonaoxahentriacontanedioic acid
- Bis-PEG9-COOH
- Bis-PEGn-CH2CH2COOH (n=9,25)
- HOOC-PEG8-COOH
- HOOCCH2CH2O-PEG8-CH2CH2COOH
- COOH-PEG8-COOH
- α,ω-dipropionic acid octaethylene glycol
- Bis-PEG25-acid
- Bis-PEG10-acid
- HOOCCH2CH2-PEG24-CH2CH2COOH
