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Azido-PEG11-alcohol

Azido-PEG11-alcohol Structure
Azido-PEG11-alcohol
  • CAS No.2252392-53-1
  • Chemical Name:Azido-PEG11-alcohol
  • CBNumber:CB13134154
  • Molecular Formula:C22H45N3O11
  • Formula Weight:527.61
  • MOL File:2252392-53-1.mol
Azido-PEG11-alcohol Property
  • solubility Soluble in Water, DMSO, DCM, DMF
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

Azido-PEG11-alcohol Chemical Properties,Usage,Production

  • Description Azido-PEG11-alcohol is a monodisperse linear PEG linker. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
  • Uses Azido-PEG11-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG11-alcohol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
  • IC 50 PEGs
  • References [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG11-alcohol Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG11-alcohol Suppliers
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Azido-PEG11-alcohol Spectrum
2252392-53-1, Azido-PEG11-alcoholRelated Search:
  • 抑制剂
  • PEG系列产品-N3-PEG系列
  • 叠氮-十一聚乙二醇-乙醇
  • 叠氮-十一聚乙二醇
  • 2252392-53-1
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  • Azido-PEG11-alcohol

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