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GNE-955

GNE-955 Structure
GNE-955
GNE-955 Property
  • Boiling point 615.2±55.0 °C(Predicted)
  • Density 1.43±0.1 g/cm3(Predicted)
  • storage temp. Store at -20°C
  • solubility Soluble in DMSO
  • pka 9.90±0.20(Predicted)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

GNE-955 Chemical Properties,Usage,Production

  • Description GNE-955 is a Potent Pan-Pim Inhibitor. GNE-955 is potent and has excellent bioavailability in rat.
  • Uses GNE-955 is a potent and orally active pan Pim kinase inhibitor with Kis of 0.018, 0.11, 0.08 nM for Pim1, Pim2, Pim3, respectively.
  • IC 50 PIM1: 0.018 nM (Ki); PIM2: 0.11 nM (Ki); PIM3: 0.08 nM (Ki)
  • References [1] Wang X, et al. Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized Bioavailability. J Med Chem. 2017 May 25;60(10):4458-4473. DOI:10.1021/acs.jmedchem.7b00418
GNE-955 Preparation Products And Raw materials
Raw materials
Preparation Products
GNE-955 Suppliers
Global(15)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel： +8613564774135
  • Email：zijue.cai@tsbiochem.com
  • Country：United States
  • ProdList：19881
  • Advantage：58
  • Supplier： DC Chemicals
  • Tel：021-58447131<br/>13564518121
  • Email：sales@dcchemicals.com
  • Country：China
  • ProdList：9409
  • Advantage：58
GNE-955 Spectrum
1527523-39-2, GNE-955Related Search:
  • 抑制剂
  • 对照品
  • 化合物 GNE-955
  • 化合物 T15406
  • 1527523-39-2
  • (3S)-1-[3-Methoxy-6-[6-(6-methylpyrazin-2-yl)pyrazolo[4,3-c]pyridin-1-yl]pyridin-2-yl]piperidin-3-amine
  • 3-Piperidinamine, 1-[3-methoxy-6-[6-(6-methyl-2-pyrazinyl)-1H-pyrazolo[4,3-c]pyridin-1-yl]-2-pyridinyl]-, (3S)-
  • GNE955,GNE 955
  • GNE-955( 5-Azaindazole)
  • GNE-955

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