ChemicalBook > CAS DataBase List > D-(+)-Glucono-1,5-lactone

D-(+)-Glucono-1,5-lactone

Description

CAS No.90-80-2
Chemical Name:D-(+)-Glucono-1,5-lactone
CBNumber:CB4494337
Molecular Formula:C6H10O6
Formula Weight:178.14
MOL File:90-80-2.mol

D-(+)-Glucono-1,5-lactone Property

Melting point 160 °C (dec.)(lit.)
Boiling point 230.35°C (rough estimate)
alpha 65 º (c=1,H2O)
Density 0.6
bulk density 750kg/m3
refractive index 63.5 ° (C=10, H2O)
storage temp. Sealed in dry,Room Temperature
solubility 590g/l Hydrolysis
form Crystalline Powder
pka 12.06±0.60(Predicted)
color White to off-white
PH 3.6 (10g/l, H2O, 20℃)
Odor wh. cryst. powd., pract. odorless
biological source microbial
Water Solubility 500 g/L (20 ºC)
Merck 14,4457
BRN 83286
LogP -2.38
CAS DataBase Reference 90-80-2(CAS DataBase Reference)
FDA 21 CFR 184.1318; 155.120
Substances Added to Food (formerly EAFUS) GLUCONO-DELTA LACTONE
EWG's Food Scores 1
FDA UNII WQ29KQ9POT
NIST Chemistry Reference D-Gluconic acid, «delta»-lactone(90-80-2)
EPA Substance Registry System .delta.-Gluconolactone (90-80-2)
UNSPSC Code 41116107
NACRES NA.79

Safety

Hazard Codes :Xn,Xi
Risk Statements :21-36/38-46-62-63
Safety Statements :24/25-53-36/37-26-25
WGK Germany :3
RTECS :LZ5184000
F :21
TSCA :Yes
HS Code :29322090
Hazardous Substances Data :90-80-2(Hazardous Substances Data)

NFPA 704:

	1
0		1

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319
Precautionary statements P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

D-(+)-Glucono-1,5-lactone Price More Price(15)

Brand: Sigma-Aldrich(India)
Product number: G4750
Product name : D-(+)-Gluconic acid δ-lactone
Purity: ≥99.0%
Packaging: 100G
Price: ₹6116.13
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: G4750
Product name : D-(+)-Gluconic acid δ-lactone
Purity: ≥99.0%
Packaging: 500G
Price: ₹8281.13
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: G4750
Product name : D-(+)-Gluconic acid δ-lactone
Purity: ≥99.0%
Packaging: 1KG
Price: ₹15966.88
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: G2164
Product name : Gluconolactone
Purity: meets USP testing specifications
Packaging: 100G
Price: ₹2511.4
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: G2164
Product name : Gluconolactone
Purity: meets USP testing specifications
Packaging: 1KG
Price: ₹7296.05
Updated: 2022/06/14
Buy: Buy

D-(+)-Glucono-1,5-lactone Chemical Properties,Usage,Production

Description Delta-Gluconolactone (GDL) is a lactone of the D-gluconate. It is a natural constituent of many foods. It can be found in honey, fruit juices, wine and many-fermented products1-3. It is used as a food additive with the E number E575 used as a sequestrant, an acidifier (it lower the pH and also help preserve the food from deterioration by enzymes and organisms), or a curing, pickling, or leavening agent. GDL has been marketed for use in feta cheese. GDL is neutral, but hydrolyses in water to gluconic acid that is acidic, adding a tangy taste to foods, though it has roughly a third of the sourness of citric acid. It can be used as nutritional supplement in beverage such as in Instant Drinks, Syrups, RTD Tea and Coffee, Sports and Energy Drinks, Waters.
Description Glucono delta-lactone (C6H10O6), molecular weight 178.14, is an inner ester of gluconic acid. Commonly named gluconolactone, other synonyms include D-gluconic acid delta-lactone, D-glucono- 1, 5-lactone, and D-delta-gluconolactone. Some of its earliest uses as a food ingredient were as a flavoring (e.g., sherbets) and to reduce fat absorption in doughnuts and cones. Glucono deltalactone tastes sweet initially and has a slightly acid-aftertaste.
Chemical Properties Powder
Uses Geogard(R)Ultra is a synergistic blend of gluconolactone and sodium benzoate. This blend provides broad spectrum protection against product spoilage in a variety of personal care formulations. Product Data Sheet
Uses (GDL) An acidulant. It hydrolyzes to form gluconic acid in water solution and thereby creates the desired pH. The rate of acid formation is affected by temperature, concentration, and the pH of the solution. It has low acid release at room temperature and accelerated conversion into gluconic acid at high temperatures. It is readily soluble with a solubility of 59 g in 100 ml of water at 20°C. It functions as a leavening agent, acidulant, curing and pickling agent, and pH control agent. It is comparatively less tart/sour than other food acids. It is used in baked goods, fish products, desserts, and dressings.
Uses gluconolactone is used in cosmetics for its anti-acne properties. It can also help improve skin hydration given its water-binding ability. In addition, formulators may select gluconolactone for its action as a product stabilizer (chelating agent). Some studies indicate potential free-radical scavenging capacities as well. These properties would make it particularly relevant for use in making anti-aging, moisturizing, and possibly sun care products.
Uses a product of the oxidation of glucose by glucose oxidase
Uses A lactone (cyclic ester) of D-gluconic acid used as a used as a sequestrant, an acidifier, or a curing, pickling, or leavening agent.
Uses D-glucono-1,5-lactone is the lactone derivative of D-gluconic acid. D-glucono-1,5-lactone is widely used as a food additive to achieve a curing, pickling or leavening effect.
Uses Component of many cleaning cmpds because of the sequestering ability of the gluconate radical which remains active in alk solutions; in the dairy industry to prevent milkstone; in breweries to prevent beerstone; as latent acid catalyst for acid colloid resins, particularly in textile printing; as a coagulant for tofu.
Definition ChEBI: D-glucono-1,5-lactone is an aldono-1,5-lactone obtained from D-gluconic acid. It has a role as an animal metabolite and a mouse metabolite. It is a gluconolactone and an aldono-1,5-lactone. It is functionally related to a D-gluconic acid.
Preparation Glucono delta-lactone is prepared commercially by the oxidation of glucose with bromine water.
General Description Gluconolactone is a non-toxic component of the skin. It has anti-oxidant and free radical scavenging effects. Gluconolactone has antiaging and skin-firming properties. It acts as a?β-glucosidase inhibitor. Gluconolactone stimulates cellulase gene expression.
Flammability and Explosibility Non flammable
Biochem/physiol Actions Glucono-d-lactone increased the doubling time and activated enzymes involved in the oxidative pentose phosphate pathway of Saccharomyces cerevisiae.
Safety Profile Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.
Purification Methods Crystallise Dglucono-lactone from ethylene glycol monomethyl ether and dry for 1hour at 110o. It can be freed from other sugars via a column of Celite and charcoal (750g of each, 90 x 7.5cm) which is washed with 0.01N formic acid until the pH of the wash is equal to that of the entering acid. The lactone is applied in H2O and eluted with 0.01N formic acid (7L), then eluted with 7.5% EtOH/0.01N formic acid (8L), then 15% EtOH/0.01N formic acid (8L) which removes pentose and isomaltose (the optical rotation of the eluates are used for sugar detection) and finally elution with aqueous formic acid provides glucolactone which is obtained by evaporating or freeze drying. Its solubility in H2O is 60% and 1% in EtOH. A solution in H2O is slightly acidic, and the lactone dissolves in an equivalent of aqueous NaOH to form sodium D-gluconate [527-07-1] M 218.1, m 2002 0 6o(dec), [ ] D 25 +12o (c 10, H2O), pK2 5 3.6. [cf p 553, Smith & Whelan Biochemical Preparations 10 127 1963, Beilstein 3 IV 1255.]