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D-Glucurone

CAS No.32449-92-6
Chemical Name:D-Glucurone
CBNumber:CB9718232
Molecular Formula:C6H8O6
Formula Weight:176.12
MOL File:32449-92-6.mol

D-Glucurone Property

Melting point 172-175 °C (lit.)
Boiling point 227.71°C (rough estimate)
alpha 19 º (c=10, H2O)
Density 1,76 g/cm³
refractive index 18.5 ° (C=5, H2O)
storage temp. Store below +30°C.
solubility water: soluble25mg/mL, clear, colorless
form Crystals or Crystalline Powder
pka 11.96±0.60(Predicted)
color White
Odor at 100.00 %. very mild mentholic
Odor Type mentholic
optical activity [α]24/D +18.8°, c = 8 in H2O
Water Solubility SOLUBLE
Merck 14,4467
BRN 83595
InChIKey OGLCQHRZUSEXNB-IEPORWDDSA-N
LogP -3.457 (est)
CAS DataBase Reference 32449-92-6(CAS DataBase Reference)
FDA UNII XE4Y3016M9
EPA Substance Registry System D-Glucuronolactone (32449-92-6)
UNSPSC Code 85151701
NACRES NA.24

Safety

Hazard Codes :Xi
Risk Statements :36/37/38
Safety Statements :24/25-36-26
WGK Germany :2
RTECS :LZ8930000
TSCA :Yes
HS Code :29322980

NFPA 704:

	1
0		0

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal wordWarning
Hazard statements H315-H319
Precautionary statements P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

D-Glucurone Price More Price(9)

Brand: Sigma-Aldrich(India)
Product number: 851450
Product name : D-(+)-Glucuronic acid γ-lactone
Purity: ≥99%
Packaging: 100G
Price: ₹5131.05
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 851450
Product name : D-(+)-Glucuronic acid γ-lactone
Purity: ≥99%
Packaging: 1KG
Price: ₹18586.53
Updated: 2022/06/14
Buy: Buy

Brand: Sigma-Aldrich(India)
Product number: 05566
Product name : D-(+)-Glucuronic acid γ-lactone
Purity: analytical standard
Packaging: 100MG
Price: ₹6365.1
Updated: 2022/06/14
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Brand: TCI Chemicals (India)
Product number: G0055
Product name : D-Glucurono-6,3-lactone
Purity:
Packaging: 25G
Price: ₹2400
Updated: 2022/05/26
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Brand: TCI Chemicals (India)
Product number: G0055
Product name : D-Glucurono-6,3-lactone
Purity:
Packaging: 100G
Price: ₹4800
Updated: 2022/05/26
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D-Glucurone Chemical Properties,Usage,Production

Chemical Properties white crystals or crystalline powder
Uses D-Glucurono-6,3-lactone is a glucuronic acid derivative studied for its effectiveness against canine hepatitis. It is utilized in the studies such as starting regent in the synthesis of 2,3,4,-tris(tert.-butyldimethysilyl) glucuronic acid trichloroethylester, required for the preparation of 1-O-acyl glucuronide of the anti-inflammatory drug ML-3000, synthesis of optically active glucopyranoses, synthesis of long-chain alkyl glucofuranosides.
Uses D-Glucurone is a glucuronic acid derivative. It is used for treating canine hepatitis.
Definition The γ-lactone of glucuronic acid. Found in plant gums and animal connective tissues.
General Description D-(+)-Glucuronic acid γ-lactone (Glucourono-γ-lactone, Glucurone or Glycurone) is a carbohydrate derivative. It converted into L-ascorbic acid in animals and human body. Its molecule contains two five-membered rings. Its crystal structure has been studied.
Purification Methods Dissolve the lactone or mixture of lactone and acid in H2O and concentrate on a steam bath until crystallisation begins. Cool rapidly to room temperature wih stirring. After 2hours the product is filtered off, washed with cold EtOH and dried to m 174-175o and [] D +19.8o (c 5.2, H2O). The amount of free acid can be obtained by titration of an ice-cold aqueous solution with standard alkali. It can be recrystallised from EtOH, EtOH/H2O or MeOH, and the highest recorded m is 180o. [Stacey J Chem Soc 1529 1939, Mehltretter et al. J Am Chem Soc 73 2424 1951, Beilstein 18 III/IV 3055, 18/5 V 33.]