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Desoxycorticosterone

Desoxycorticosterone Structure
Desoxycorticosterone
  • CAS No.64-85-7
  • Chemical Name:Desoxycorticosterone
  • CBNumber:CB4314147
  • Molecular Formula:C21H30O3
  • Formula Weight:330.46
  • MOL File:64-85-7.mol
Desoxycorticosterone Property
  • Melting point 138-144 °C
  • alpha 184 º (c=1, C2H5OH)
  • Boiling point 407.89°C (rough estimate)
  • Density 1.0998 (rough estimate)
  • refractive index 1.5192 (estimate)
  • Flash point 9℃
  • storage temp. -20°C
  • solubility Chloroform (Slightly), Methanol (Slightly)
  • form Solid
  • pka 12.98±0.10(Predicted)
  • color White to Pale Yellow
  • optical activity +17822 (c 1.5, ethanol)
  • Water Solubility slightly soluble
  • Merck 13,2917
  • BRN 2062123
  • LogP 2.880
  • CAS DataBase Reference 64-85-7(CAS DataBase Reference)
  • EWG's Food Scores 1
  • FDA UNII 40GP35YQ49
  • ATC code H02AA03
  • NIST Chemistry Reference Deoxycorticosterone(64-85-7)
  • EPA Substance Registry System Deoxycorticosterone (64-85-7)
  • UNSPSC Code 41116107
  • NACRES NA.24
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H351-H373
  • Precautionary statements P201-P308+P313
Desoxycorticosterone Price More Price(4)
  • Brand: Sigma-Aldrich(India)
  • Product number: D6875
  • Product name : 21-Hydroxyprogesterone
  • Purity: ≥97% (HPLC)
  • Packaging: 500MG
  • Price: ₹21595.88
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D6875
  • Product name : 21-Hydroxyprogesterone
  • Purity: ≥97% (HPLC)
  • Packaging: 1G
  • Price: ₹35841.58
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D6875
  • Product name : 21-Hydroxyprogesterone
  • Purity: ≥97% (HPLC)
  • Packaging: 5G
  • Price: ₹126804.05
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: D-105
  • Product name : 11-Deoxycorticosterone solution
  • Purity: 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging: 1ML
  • Price: ₹15374.8
  • Updated: 2022/06/14
  • Buy: Buy

Desoxycorticosterone Chemical Properties,Usage,Production

  • Chemical Properties white to creamy-white crystalline powder
  • Uses Antiinflammatory;Corticoide
  • Uses A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).
  • Definition ChEBI: A mineralocorticoid that is progesterone substituted at position 21 by a hydroxy group.
  • General Description 11-Deoxycorticosterone is a steroid hormone produced in the adrenal glands that acts as a precursor for the hormone aldosterone. Levels of 11-deoxycorticosterone are measured by LC-MS/MS to aid in diagnosing disorders of steroid synthesis, such as 11-hydroxylase deficiency and glucocorticoid responsive hyperaldosteronism. This Certified Spiking Solution? is suitable for use as starting material inlinearity standards, calibrators, and controls for numerous LC-MS/MS applications in endocrinology, clinical chemistry, and neonatal screening.
  • Hazard Toxic.
  • Mechanism of action Desoxycorticosterone causes an increase in reabsorption of sodium ions and excretion of potassium ions from the renal tubules, which leads to increased tissue hydrophilicity. This facilitates an elevated volume of plasma and increased arterial pressure. Muscle tonicity and work capability are increased. It is used for an insufficiency of function of the adrenal cortex, myasthenia, asthenia, adynamia, and overall muscle weakness.
  • Synthesis Desoxycorticosterone, 21-hydroxypregn-4-en-3,20-dione acetate (27.2.6), is synthesized in a number of ways, the easiest of which being iodination of progesterone at C21 in the methyl group, and subsequent reaction of the resulting iodo-derivative 27.2.5 with potassium acetate, which leads to formation of the desired desoxycorticosterone in the form of the acetate (27.2.6) .

    Synthesis_64-85-7

  • Purification Methods Crystallise 11-deoxycorticosterone from diethyl ether. [Schindler et al. Helv Chim Acta 24 360 1941, Steiger & Reichstein Helv Chim Acta 20 1164 1937.]
Desoxycorticosterone Preparation Products And Raw materials
Raw materials
Preparation Products
Desoxycorticosterone Suppliers
Global(156)Suppliers
  • Supplier：
    TargetMol Chemicals Inc.
  • Tel：+1-781-999-5354<br/>+1-00000000000
  • Email：marketing@targetmol.com
  • Country：United States
  • ProdList：32159
  • Advantage：58
  • Supplier：
    Aladdin Scientific
  • Tel：
  • Email：tp@aladdinsci.com
  • Country：United States
  • ProdList：57505
  • Advantage：58
Desoxycorticosterone Spectrum
64-85-7, DesoxycorticosteroneRelated Search:
  • Steroids
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • 生化试剂
  • 临床检测标准物质
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  • 医药、农药及染料中间体
  • 其他原料药
  • 医药原料
  • 合成
  • 甾体激素 (激素，糖皮激素)
  • 甾体激素类
  • 去氧皮质酮,10 MM DMSO 溶液
  • 乙腈中去氧皮质酮
  • 甲醇中去氧皮质酮溶液标准物质
  • 甲醇中11去氧皮质酮
  • 21Α-羟基孕酮
  • 21Α-羟基孕酮/去氧皮质酮标准品
  • 11-去氧皮质酮/21-羟基孕酮
  • 2H4] -11-脱氧皮质酮
  • 皮质酮杂质5
  • 去氧皮质酮 100UG/ML溶于甲醇
  • 去氧皮质酮(2,3,4-13C3,99%)100 UG/ML 溶于甲醇
  • 2H6]-脱氧皮质酮
  • 13C2,2H2]-脱氧皮质酮
  • 脱氧曲线酮
  • 去氧皮质酮(2,3,4-13C3,99%)
  • 去氧皮质酮 未标记
  • 11-脱氧皮质酮 (溶液)
  • 11-脱氧皮质酮
  • 21Α-羟基孕酮/去氧皮质酮 标准品
  • 去氧皮质酮 标准品
  • 21-羟基孕酮
  • 孕甾-4-烯-21-醇-3,20-二酮
  • 脱氧肾上腺皮质甾酮
  • 脱氧皮质甾酮
  • 脱氧皮质酮
  • 去氧皮质脂酮
  • 11-脱氧肾上腺皮质甾酮
  • 去氧皮甾酮
  • 去氧皮质甾酮
  • 羟基孕酮/去氧皮质酮
  • 去氧皮质酮
  • 21-羟基孕甾-4-烯-3,20-二酮
  • 21-羟基黄体酮
  • 11-去氧皮质酮
  • 去氧皮质酮溶液,100PPM
  • 64-85-7
  • (8S,9S,10R,13S,14S,17S)-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • Deoxycorticosterone, 10 mM in DMSO
  • 2H4]-11-Deoxycorticosterone
  • 2H6]-Deoxycorticosterone
  • 13C2,2H2]-Deoxycorticosterone
  • 21-hydroxyprogesteroneQ: What is 21-hydroxyprogesterone Q: What is the CAS Number of 21-hydroxyprogesterone Q: What is the storage condition of 21-hydroxyprogesterone
  • Desoxycorticosterone USP/EP/BP
  • 11-Deoxycorticosterone-2,3,4-13C3 solution 100 mug/mL in methanol, >=99 atom % 13C, >=98% (CP)
  • Corticosterone Impurity 5

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