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Hydrocortisone sodium succinate

Hydrocortisone sodium succinate Structure
Hydrocortisone sodium succinate
  • CAS No.125-04-2
  • Chemical Name:Hydrocortisone sodium succinate
  • CBNumber:CB0373175
  • Molecular Formula:C25H33O8.Na
  • Formula Weight:484.52
  • MOL File:125-04-2.mol
Hydrocortisone sodium succinate Property
  • Melting point 169.0-171.2°
  • storage temp. −20°C
  • solubility H2O: 50 mg/mL
  • form powder
  • color White to Off-White
  • biological source synthetic (organic)
  • Water Solubility H2O: 50mg/mL
  • InChIKey HHZQLQREDATOBM-CODXZCKSSA-M
  • CAS DataBase Reference 125-04-2(CAS DataBase Reference)
  • FDA UNII 50LQB69S1Z
  • NCI Drug Dictionary A-Hydrocort
  • UNSPSC Code 12352209
  • NACRES NA.77
Safety
  • WGK Germany  :3
  • RTECS  :GM9015000
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H361d
  • Precautionary statements P201-P308+P313
Hydrocortisone sodium succinate Price More Price(3)
  • Brand: Sigma-Aldrich(India)
  • Product number: H4881
  • Product name : Hydrocortisone 21-hemisuccinate sodium salt
  • Purity: ≥90% (HPLC)
  • Packaging: 100MG
  • Price: ₹3712.98
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: H4881
  • Product name : Hydrocortisone 21-hemisuccinate sodium salt
  • Purity: ≥90% (HPLC)
  • Packaging: 1G
  • Price: ₹18207.65
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: H2270
  • Product name : Hydrocortisone 21-hemisuccinate sodium salt
  • Purity: powder, BioReagent, suitable for cell culture
  • Packaging: 100MG
  • Price: ₹4351.65
  • Updated: 2022/06/14
  • Buy: Buy

Hydrocortisone sodium succinate Chemical Properties,Usage,Production

  • Uses Hydrocortisone Hemisuccinate Sodium is a derivative of the glucocorticoid Hydrocortisone (H714615). Hydrocortisone Hemisuccinate Sodium is used as an anti-inflammatory agent. Hydrocortisone Hemisuccinate Sodium is widely used in the treatment of asthma, endocrine disorders, dermatological disorders, allergic states, etc.
  • Uses Hydrocortisone 21-hemisuccinate is a water-soluble form of the endogenous hormone cortisol. It can bind to glucocorticoid receptors, initiating the transcription of anti-inflammatory and immunosuppressive mediators and inhibiting proinflammatory cytokine activity (IC50 = 6.7 μM for IL-6). It is commonly used to supplement media for long-term epithelial or endothelial cell cultures and to differentiate pluripotent stem cells.
  • Uses Hydrocortisone sodium succinate is a derivative of the glucocorticoid Hydrocortisone (H714615). Hydrocortisone Hemisuccinate Sodium is used as an anti-inflammatory agent. Hydrocortisone sodium succinate is widely used in the treatment of asthma, endocrine disorders, dermatological disorders, allergic states, etc.
  • Definition ChEBI: Hydrocortisone Sodium Succinate is an organic molecular entity.
  • brand name A-Hydrocort (Abbott); A-Hydrocort (Hospira); Solu-Cortef (Pharmacia & Upjohn).
  • General Description Hydrocortisone for use in epithelial and endothelial adherent cell culture applications.
  • Drug interactions Potentially hazardous interactions with other drugs
    Aldesleukin: avoid concomitant use.
    Antibacterials: metabolism accelerated by rifampicin; metabolism possibly inhibited by erythromycin; concentration of isoniazid possibly reduced.
    Anticoagulants: efficacy of coumarins and phenindione may be altered.
    Antiepileptics: metabolism accelerated by carbamazepine, fosphenytoin, phenobarbital, phenytoin and primidone.
    Antifungals: increased risk of hypokalaemia with amphotericin - avoid; metabolism possibly inhibited by itraconazole and ketoconazole.
    Antivirals: concentration possibly increased by ritonavir.
    Ciclosporin: rare reports of convulsions in patients on ciclosporin and high-dose corticosteroids.
    Cobicistat: concentration of hydrocortisone possibly increased - increased risk of adrenal suppression.
    Diuretics: enhanced hypokalaemic effects of acetazolamide, loop diuretics and thiazide diuretics.
    Vaccines: high dose corticosteroids can impair immune response to vaccines - avoid concomitant use with live vaccines.
  • Metabolism Hydrocortisone is metabolised in the liver and most body tissues to hydrogenated and degraded forms such as tetrahydrocortisone and tetrahydrocortisol. These are excreted in the urine, mainly conjugated as glucuronides, with a very small proportion of unchanged hydrocortisone.
Hydrocortisone sodium succinate Preparation Products And Raw materials
Raw materials
Preparation Products
Hydrocortisone sodium succinate Suppliers
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Hydrocortisone sodium succinate Spectrum
125-04-2, Hydrocortisone sodium succinate Related Search:
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  • C25H33NaO8
  • C25H33O8Na
  • 化合物 HYDROCORTISONE SODIUM SUCCINATE
  • 氢化可的松琥珀酸钠(非无菌)
  • 氢化氨酸钠琥珀酸钠
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  • 氢化可的松琥珀酸钠HYDROCORTISONE SODIUM SUCCINATE
  • 氢可琥钠氢化可的松 21-半琥珀酸酯 钠盐
  • 氢可琥钠
  • 氢化可的松琥珀酸酯 钠盐
  • 氢化可的松 21-半琥珀酸酯 钠盐
  • 11Β,17Α,21-TRIHYDROXY-4-PREGNENE-3,20-DIONE 21-HEMISUCCINATE 钠盐
  • 皮質醇
  • 氢化可的松琥珀酸钠
  • 125-04-2
  • Hydrocortisone hemisuccinate sodium
  • Hydrocortisone SodiuM Succinate, Buffered 5 Percent
  • Hydrocortisone sodium succinate Powder
  • HydrocortisoneHemisuccinateSodiumSal
  • solu-cortef
  • PREGN-4-ENE-3 20-DIONE 21-(3-CARBOXY-1-O XOPROPOXY)-11 17-DIHYDROXY-MONOSODIUM SA LT (11)-CORTISOL 21-(SODIUM SUCCINATE)
  • Cortop
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  • Hydrocortisone sodium succinateQ: What is Hydrocortisone sodium succinate Q: What is the CAS Number of Hydrocortisone sodium succinate Q: What is the storage condition of Hydrocortisone sodium succinate Q: What are the applications of Hydrocortisone sodium succinate
  • Hydrocortisone sodium succinate USP/EP/BP
  • Hydrocortisone Sodium Succinate 125-04-2
  • 21-Sodium succinate

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