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ML-228

ML-228 Structure
ML-228
ML-228 Property
  • Boiling point 686.0±65.0 °C(Predicted)
  • Density 1.228±0.06 g/cm3(Predicted)
  • storage temp. -20°C, Inert atmosphere
  • solubility DMSO (Slightly), Methanol (Slightly)
  • form Solid
  • pka 2.03±0.63(Predicted)
  • color Pale Yellow to Light Yellow
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements

ML-228 Chemical Properties,Usage,Production

  • Uses N-([1,1''-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine is an activator of the hypoxia inducible factor (HIF) pathway.
  • Definition ChEBI: ML228 is a member of the class of 1,2,4-triazines in which the triazine ring is substituted at positions 3, 5, and 6 by pyridin-2-yl, ([biphenyl]-4-ylmethyl)amin, and methyl groups, respectively. It is an activator of the hypoxia inducible factor (HIF) pathway. It has a role as a hypoxia-inducible factor pathway activator. It is a member of biphenyls, a member of 1,2,4-triazines, a secondary amino compound and a member of pyridines.
  • in vivo

    ML228 (injection; 1 μg/kg; 7 days) treatments following spinal cord injury (SCI) improves the local hypoxic ischemia environment, reduce SCI secondary injury and promote the recovery of neurological function[3].

    Animal Model:SD rat[3]
    Dosage:1 μg/kg
    Administration:injection; 7 days
    Result:Alleviated SCI of the central nervous system and relieve associated symptoms.
ML-228 Preparation Products And Raw materials
Raw materials
Preparation Products
ML-228 Suppliers
Global(81)Suppliers
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    TargetMol Chemicals Inc.
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    Aladdin Scientific
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ML-228 Spectrum
1357171-62-0, ML-228Related Search:
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  • 抑制剂
  • 高端化学
  • C27H21N5
  • 化合物ML228,10 MM DMSO 溶液
  • N-([1,1′-联苯基]-4-基甲基)-6-苯基-3-(2-吡啶基)-1,2,4-三嗪-5-胺
  • ML 228,HIF通路激活剂
  • 化合物ML228
  • 1357171-62-0
  • ML228, 10 mM in DMSO
  • 1,2,4-Triazin-5-amine, N-([1,1'-biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-
  • L-228
  • ML-228;CID-46742353
  • CID-46742353
  • N-([1,1'Biphenyl]-4-ylmethyl)-6-phenyl-3-(2-pyridinyl)-1,2,4-triazin-5-amine
  • ML228; ML 228
  • N-([1,1-Biphenyl]-4-ylmethyl)-6-phenyl-3-(pyridin-2-yl)-1,2,4-triazin-5-amine
  • ML-228

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