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psoralidin

psoralidin Structure
psoralidin
  • CAS No.18642-23-4
  • Chemical Name:psoralidin
  • CBNumber:CB41384552
  • Molecular Formula:C20H16O5
  • Formula Weight:336.34
  • MOL File:18642-23-4.mol
psoralidin Property
  • Melting point 290-292°
  • Boiling point 458.8±34.0 °C(Predicted)
  • Density 1.383±0.06 g/cm3(Predicted)
  • storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
  • solubility DMSO: soluble5mg/mL, clear (warmed)
  • form powder
  • pka 8.70±0.20(Predicted)
  • color white to beige
  • InChIKey YABIJLLNNFURIJ-UHFFFAOYSA-N
  • FDA UNII G16ZUQ069L
  • UNSPSC Code 41116107
  • NACRES NA.77
Safety
  • WGK Germany  :3
  • HS Code  :2932.20.4500
  • NFPA 704:
    0
    2 0
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordWarning
  • Hazard statements H302
  • Precautionary statements P301+P312+P330
psoralidin Price More Price(4)
  • Brand: Sigma-Aldrich(India)
  • Product number: SML0932
  • Product name : Psoralidin
  • Purity: ≥98% (HPLC)
  • Packaging: 5MG
  • Price: ₹8605.88
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: Sigma-Aldrich(India)
  • Product number: SML0932
  • Product name : Psoralidin
  • Purity: ≥98% (HPLC)
  • Packaging: 25MG
  • Price: ₹34878.15
  • Updated: 2022/06/14
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: P2605
  • Product name : Psoralidin
  • Purity: 
  • Packaging: 25MG
  • Price: ₹7800
  • Updated: 2022/05/26
  • Buy: Buy
  • Brand: TCI Chemicals (India)
  • Product number: P2605
  • Product name : Psoralidin
  • Purity: 
  • Packaging: 100MG
  • Price: ₹28200
  • Updated: 2022/05/26
  • Buy: Buy

psoralidin Chemical Properties,Usage,Production

  • Description Psoralidin is a furanocoumarin isolated from the seeds of P. corylifolia, a medicinal plant found in southeastern Asia, that has been shown to induce cytotoxicity against various cancer cells. Through TNF-related apoptosis-inducing ligand-mediated events, psoralidin at 50 μM can induce the death of HeLa cancer cells. It also can induce apoptosis of androgen-dependent (LNCaP, C4-2B) and androgen-independent (DU-145, PC-3) prostate cancer cells and inhibit the growth of PC-3 xenograft tumors in nude mice.
  • Uses Psoralidin is an antibacterial and antioxidant reagent.
  • Definition ChEBI: A member of the class of coumestans that is coumestan substituted by hydroxy groups at positions 3 and 9 and a prenyl group at position 2 respectively.
  • in vivo

    Psoralidin (5 mg/kg) regulates expression of pro-inflammatory cytokines that play an important role in inflammatory diseasesin IR-irradiated lung of BALB/c mouse[1].

    Animal Model:BALB/c mice[1]
    Dosage:5 mg/kg
    Administration:Intraperitoneal application; 30 min before and 1 h after IR irradiation (20 Gy).
    Result:Anti-inflammatory effect in IR-irradiated mice.
  • IC 50 COX-2; 5-LOX
  • References [1] yang h j, youn h s, seong k m, et al. psoralidin, a dual inhibitor of cox-2 and 5-lox, regulates ionizing radiation (ir)-induced pulmonary inflammation[j]. biochemical pharmacology, 2011, 82(5): 524-534.
    [2] chiou w f, don m j, liao j f, et al. psoralidin inhibits lps-induced inos expression via repressing syk-mediated activation of pi3k-ikk-iκb signaling pathways[j]. european journal of pharmacology, 2011, 650(1): 102-109.
    [3] bronikowska j, szliszka e, jaworska d, et al. the coumarin psoralidin enhances anticancer effect of tumor necrosis factor-related apoptosis-inducing ligand (trail)[j]. molecules, 2012, 17(6): 6449-6464.
psoralidin Preparation Products And Raw materials
Raw materials
Preparation Products
psoralidin Suppliers
Global(214)Suppliers
  • Supplier：
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  • Tel：+86-0371-86658258<br/>+8613203830695
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  • Advantage：58
  • Supplier：
    BOC Sciences
  • Tel：+1-631-485-4226
  • Email：inquiry@bocsci.com
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  • ProdList：19552
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psoralidin Spectrum
18642-23-4, psoralidinRelated Search:
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  • 补骨脂系列
  • PSORALIDIN 补骨脂定/补骨酯定 |CAS 18642-23-4
  • 补骨脂定,10 MM DMSO 溶液
  • 补骨脂定/香豆素类
  • 标准品对照品】PSORALIDIN
  • 3,9-二羟基-2-(3-甲基丁-2-烯-1-基)-6H-苯并呋喃并[3,2-C]苯并吡喃-6-酮
  • 补骨脂定对照品
  • 补骨脂啶
  • PSORALIDIN 补骨脂定 标准品
  • 补骨脂定, BR
  • PSORALIDIN 补骨脂定
  • 补骨脂定
  • 补骨脂定(标准品)
  • 补骨酯定
  • 18642-23-4
  • Psoralidin, 10 mM in DMSO
  • Psoralidin-RM
  • Psoralidin (6CI)
  • 3,9-dihydroxy-2-(3-methylbut-2-enyl)-[1]benzofuro[3,2-c]chromen-6-one
  • 3,9-Dihydroxy-2-(3-methylbut-2-en-1-yl)-6H-benzofuro[3,2-c]chromen-6-one
  • 6H-Benzofuro[3,2-c][1]benzopyran-6-one, 3,9-dihydroxy-2-(3-methyl-2-buten-1-yl)-
  • Psoralidin, BR
  • Psorslidin
  • 3,9-Dihydroxy-2-(3-methyl-2-butenyl)-6H-benzofuro[3,2-c][1]benzopyran-6-one
  • psoralidin
  • Psoralidin, >=99%
  • 3,9-Dihydroxy-2-prenylcoumestan

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