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Hydrocortisone Structure

Hydrocortisone

Chemical Properties

Melting point 211-214 °C(lit.)
alpha  166 º (c=1, C2H5OH 25 ºC)
Boiling point 414.06°C (rough estimate)
Density  1.0812 (rough estimate)
refractive index  1.6120 (estimate)
Flash point 220°C
storage temp.  -20°C
solubility  H2O: 100 mg/mL
form  powder
color  White
Water Solubility  319.7mg/L(25 ºC)
Decomposition  220 ºC
Merck  14,4787
BRN  1354819
Stability Stable, but may be light sensitive. Incompatible with strong oxidizing agents.
LogP 1.610
CAS DataBase Reference 50-23-7(CAS DataBase Reference)
EWG's Food Scores 1
NCI Dictionary of Cancer Terms cortisol; hydrocortisone
FDA UNII WI4X0X7BPJ
NCI Drug Dictionary Aeroseb-HC
ATC code A01AC03,A07EA02,C05AA01,D07AA02,D07XA01,H02AB09,R01AD60,S01BA02,S01CB03,S02BA01
NIST Chemistry Reference Hydrocortisone(50-23-7)
EPA Substance Registry System Hydrocortisone (50-23-7)

Safety

Symbol(GHS) GHS hazard pictograms
Signal wordDanger
Hazard statements H360Df-H373
Precautionary statements P202-P260-P280-P308+P313-P405-P501
Hazard Codes  Xn
Risk Statements  62-63
Safety Statements  36/37
WGK Germany  3
RTECS  GM8925000
TSCA  Yes
HS Code  29372100
Hazardous Substances Data 50-23-7(Hazardous Substances Data)
Toxicity LD50 subcutaneous in mouse: > 500mg/kg
NFPA 704:
1
2 0

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