Chemical Properties
In water, methanol, ethanol, chloroform, stupid, insoluble in ether. Derived from the bean root acacia plant bitter cucumber (Sophra flavescens Ait.).
Uses
Oxysophocarpine is an alkaloid extract from Siphocampylus verticillatus it maintains anti-nociceptive effects through systemic and intracerebroventricular administration in rodents. Derivative of Sophocarpine (S676825), an antiviral agent.
Synthesis
Extraction from wolfsbane flowers:
1) Pretreatment: Soaking with a mushroom filtrate.
2) Extraction: Sequential extraction with organic solvents and dilute acetic acid solution. The extracts are combined.
3) Water precipitation: The extract is diluted with water, pH adjusted to 11, and filtered after standing.
4) Purification: The filtrate is concentrated, then purified via silica column, ether crystallization, and acetone recrystallization.
