Uses
(Chlorodifluoromethyl)trimethylsilane, is one of the partially fluorinated compounds, which are often used for diverse applications in materials science, agrochemistry, and the pharmaceutical industry.
Reactions
(1) Difluoromethylenation of alkenes.
Refs. 1) Angew. Chem. Int. Ed. 2011, 50, 7153 –7157; 2) Chem. Commun. 2011, 47, 2411–2413.
(2) Difluoromethylenation of alkynes.
Refs. 1) Angew. Chem. Int. Ed. 2011, 50, 7153 –7157; 2) Chem. Commun. 2011, 47, 2411–2413.
(3) Difluoromethylenation of TMSCN.
Ref. J. Org. Chem. 2012, 77, 5850?5855.
(4) Difluoromethylenation of benzyl and alkylzinc halides.
Ref. Org. Lett. 2013, 15, 917 – 919.
(5) Fluorination aminocarbonylation of aldehydes
Ref. Angew. Chem. Int. Ed. 2022, e202115467
