Chemical Properties
white to light yellow crystal powde
Uses
(S)-(+)-2-Phenylglycinol is a chiral arylalkylamine used as organocatalysts. Used in the synthesis and chiral recognition properties of novel fluorescent chemosensors for amino acid.
Uses
(S)-(+)-2-Phenylglycinol is used in the synthesis of chiral, unsymmetrical bisoxazolines. It is used as a reagent for the resolution of acids via the easily hydrolyzed amides.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
Enantiopure (S)-(+)-2-Phenylglycinol is produced from styrene using engineered E. coli strains that express enzyme cascades for epoxidation, hydrolysis, oxidation, and transamination[1].
References
[1]Sekar, B. S., Mao, J., Lukito, B. R., Wang, Z., & Li, Z. (2020). Bioproduction of Enantiopure (R)-and (S)-2-Phenylglycinols from Styrenes and Renewable Feedstocks. Advanced Synthesis & Catalysis, 363(7), 1892–1903.
https://doi.org/10.1002/adsc.202001322
