Chemical Properties
White to slightly yellow needles
Uses
tert-Butyl carbamate was used in palladium-catalyzed synthesis of
N-Boc-protected anilines. It was used in the synthesis of tetrasubstituted pyrroles, functionalized with ester or ketone groups at C-3 position.
Synthesis Reference(s)
The Journal of Organic Chemistry, 28, p. 3421, 1963
DOI: 10.1021/jo01047a033
General Description
Palladium-catalyzed cross-coupling reaction of
tert-butyl carbamate with various aryl(Het) halides with Cs
2CO
3 as base in 1,4-dioxane (solvent) has been investigated.