Chemical Properties
LIGHT BEIGE CRYSTALLINE POWDER
Uses
Methacetin is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.
Definition
ChEBI: Methacetin is a member of the class of acetamides that is paracetamol in which the hydrogen of phenolic hydroxy group has been replaced by a methyl group. It is a member of acetamides and an aromatic ether. It is functionally related to a p-anisidine and a paracetamol.
Synthesis Reference(s)
Journal of the American Chemical Society, 89, p. 7131, 1967
DOI: 10.1021/ja01002a061The Journal of Organic Chemistry, 42, p. 3755, 1977
Organic Syntheses, Coll. Vol. 3, p. 661, 1955
Safety Profile
Moderately toxic by ingestion andother unspecified routes. When heated to decomposition itemits toxic fumes of NOx.
