Chemical Properties
WHITE TO VERY SLIGHTLY YELLOW POWDER
Uses
N-(4-Methoxyphenyl)-3-oxobutanamide is an intermediate in the synthesis of Tafenoquine-d3 Succinate is the labelled analog of Tatenoquine (T004760), a new 8-aminoquinoline with an improved therapeutic index and safety profile as compared to primaquine (P733500).Tafenoquine has the potential to become a widely used drug in the prevention and treatment of malaria infection and could replace some currently used drugs as resistant strains of Plasmodium species increase.
Synthesis Reference(s)
The Journal of Organic Chemistry, 11, p. 803, 1946
DOI: 10.1021/jo01176a024