ChemicalBook > CAS DataBase List > D-TUBOCURARINE CHLORIDE

D-TUBOCURARINE CHLORIDE

D-TUBOCURARINE CHLORIDE Structure
D-TUBOCURARINE CHLORIDE
  • CAS No.57-94-3
  • Chemical Name:D-TUBOCURARINE CHLORIDE
  • CBNumber:CB6296605
  • Molecular Formula:C37H42Cl2N2O6
  • Formula Weight:681.65
  • MOL File:57-94-3.mol
D-TUBOCURARINE CHLORIDE Property
  • Melting point: :274~275℃
  • alpha  :D20-25 +215° (c = 0.25-0.3 g/100 ml)
  • Density  :1.2074 (rough estimate)
  • refractive index  :1.7350 (estimate)
  • storage temp.  :2-8°C
  • pka :pK: 7.4(at 25℃)
Safety
  • Hazard Codes  :T
  • Risk Statements  :25
  • Safety Statements  :45
  • RIDADR  :UN 1544 6.1/PG 2
  • WGK Germany  :3
  • RTECS  :YO4900000
  • HazardClass  :6.1(b)
  • PackingGroup  :III
  • Toxicity :LD50 in mice, rats (mg/kg): 33.2, 27.8 orally in DMSO; 59.5, 36.9 orally in water (Rosen)
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
D-TUBOCURARINE CHLORIDE Price More Price(1)
  • Brand: Sigma-Aldrich
  • Product number: 5.05145
  • Product name : (+)-Tubocurarine Chloride - CAS 57-94-3 - Calbiochem
  • Purity: 
  • Packaging: 5051450001
  • Price: $42.5
  • Updated: 2019/12/02
  • Buy: Buy

D-TUBOCURARINE CHLORIDE Chemical Properties,Usage,Production

  • Chemical Properties White to light-tan crystalline alkaloid; odorless. Mp 270C with decomposition. Soluble in water and alcohol; insoluble in acetone, chloroform, and ether; aqueous solution is strongly dextrorotatory (specific rotation for 1% solution of anhydrous ?208 to +218 degrees).
  • Uses Neuromuscular blocking agent.
  • Hazard Highly toxic.
  • Biological Activity Competitive, non-selective nicotinic acetylcholine receptor antagonist; causes skeletal muscle relaxation. Also a 5-HT 3 and GABA A receptor antagonist.
  • Safety Profile Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Human toxicity: Large doses and overdoses may cause respiratory paralysis and hypotension. When heated to decomposition it emits very toxic fumes of NOx and Cl-. Used as a muscle relaxant.
  • Purification Methods Crystallise this chloride from water. It forms various hydrates. The hydrochloride pentahydrate has m 268-269o (from H2O) and [] D +190o (0.5, H2O). Its solubility in H2O at 25o is 50mg/mL. [Beilstein 27 II 897, 27 III/IV 8727.]
D-TUBOCURARINE CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global(0)Suppliers
57-94-3, D-TUBOCURARINE CHLORIDERelated Search:
  • (+)-tubocurarinehydrochloride
  • amerizol
  • d-tubocurarinehydrochloride
  • intocostrin
  • intocostrinet
  • tubadil
  • tubarine
  • tubocurarinehydrochloride
  • 7',12'-DIHYDROXY-6,6'-DIMETHOXY-2,2',2'-TRIMETHYLTUBOCURARANIUM CHLORIDE HCL
  • TUBOCURARINE CHLORIDE, D-(RG)
  • chloride,hydrochloride,(+)-tubocurarin
  • curarin-haf
  • d-7’,12’-dihydroxy-6,6’-dimethoxy-2,2’,2’-trimethyltubocuraraniumchloride
  • delacurarine
  • dextrotubocurarinechloride
  • dichloride,(+)-tubocurarin
  • d-paracurarinechloride
  • d-tubocurarinedichloride
  • 7',12'-DIHYDROXY-6,6'-DIMETHOXY-2,2'2'-TRIMETHYLTUBOCURARARIUM CHLORIDE
  • CURARE
  • D-TUBOCURARINE CHLORIDE
  • (+)-TUBOCURARINE DICHLORIDE
  • (+)-TUBOCURARINE CHLORIDE
  • TUBOCURARINE CHLORIDE
  • TUBOCURARINE CHLORIDE, D-
  • D -TUBOCURARINE CHLORIDE CRYSTALLINE
  • (+)-tubocurarine chloride hydrate
  • TUBOCURARINE CHLORIDE, D-(P)
  • 13H-4,6:21,24-Dietheno-8, 12-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosino [2,3,4-ij]isoquinolinium, 2,3,13a,14,15,16,25,25a-octahydro- 9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl -, chlorid
  • 2,3,13a,14,15,16,25,25a,-Octahydro-9,19-dihydroxy-18,29 -dimethoxy-1,14,14-trimethyl-13H-4,6:21,24-dietheno-8,1 2-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosin o[2,3,4-ij]isoquinolinium chloride hydrochloride
  • Dextrotubocurarine chloride hydrochloride
  • d-Tubocurarine chloride hydrochloride
  • Tubocurare
  • 2,2',2'-Trimethyl-6,6'-bis(methyloxy)tubocuraran-2,2'-diium-7',12'-diol dichloride
  • 13H-4,6:21,24-Dietheno-8,12-metheno-1H-pyrido[3',2':14,15][1,11]dioxacycloeicosino[2,3,4-ij]isoquinolinium, 2,3,13a,14,15,16,25,25a-octahydro-9,19-dihydroxy-18,29-dimethoxy-1,14,14-trimethyl-, chloride, hydrochloride (1:1:1), (13aR,25aS)-
  • 57-94-3
  • C37H41ClN2O6HCl
  • C37H42Cl2N2O6
  • C37H41N2O6ClHCl
  • Alkaloids
  • Isoquinoline Alkaloids
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Ligand-Gated Ion Channels
  • Ion Channels
  • Nicotinic Acetylcholine Receptor Modulators
  • Organics
  • AntagonistsIon Channels
  • Cholinergics
  • Ligand-Gated Ion Channels
  • Neurotransmitters
  • Nicotinic Acetylcholine Receptor Modulators
  • Acetylcholine receptor
  • Nicotinic