Description
A further isoquinoline alkaloid which occurs in Salsola Richteri, the base is obtained in the form of a microcrystalline powder which is readily soluble in CHC1
3 or EtOH but only sparingly so in C
6H
6 or H
20. The alkaloid is soluble in aqueous alkalies but insoluble in petroleum ether. The hydrochloride crystallizes as the sesquihydrate in colourless needles, m.p. 14l-152°C. The N-benzoyl derivative has m.p. 172-4° and the O,N-dibenzoyl compound, m.p. 166-8°C. Treatment with CH
2N
2 gives Salsolidine (q.v.). The structure, 1:2:3:4-tetrahydro6-hydroxy-7-methoxy-l-methylisoquinoline has been confirmed by synthesis.
Uses
Salsoline (cas# 89-31-6) was identified as an analyte component in Tibetan Medicine via HPLC-Q-TOF/MS.
References
Orekhov, Proskurnina., Ber., 66,841 (1933)
Orekhov, Proskurnina., ibid, 67,878 (1934)
Spath, Orekhov, Kuffner., ibid, 67, 1214 (1934)
