Pharmacological effects Application
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Naringenin

Pharmacological effects Application
Naringenin Structure
Naringenin
  • CAS No.480-41-1
  • Chemical Name:Naringenin
  • CBNumber:CB5325311
  • Molecular Formula:C15H12O5
  • Formula Weight:272.25
  • MOL File:480-41-1.mol
Naringenin Property
Safety
  • Hazard Codes  :Xi,Xn
  • Risk Statements  :36/37/38-22
  • Safety Statements  :26-36-37/39
  • WGK Germany  :3
  • HazardClass  :IRRITANT
  • HS Code  :29329990
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
Naringenin Price More Price(2)
  • Brand: Sigma-Aldrich
  • Product number: W530098
  • Product name : Naringenin
  • Purity: natural (US), 98%
  • Packaging: SAMPLE
  • Price: $50
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: W530098
  • Product name : Naringenin
  • Purity: natural (US), 98%
  • Packaging: 500 g
  • Price: $571
  • Updated: 2021/03/22
  • Buy: Buy

Naringenin Chemical Properties,Usage,Production

  • Pharmacological effects Naringenin is the aglycone of naringin, it belongs to dihydro-flavonoids, at room temperature it is a white needle crystal(methanol), soluble in alcohol, ether and benzene, almost insoluble in water. In HCl-Mg powder reaction,it is cherry red ,in sodium borohydride reaction it is red purple, in molish reaction,it is negative. In the nature, it is mainly from the Rosaceae cherry (Prunus yedoensis Mate.) bud,and sumac plants (Amacardi-um occidentale L.)  fruits’ core-shell.
    Nucleus structure is similar among flavonoids, most of the components do not have ideal fat-soluble and water-soluble abilities, the bioavailability is low. By modifying its structure, the introduction of strongly fat-soluble or water-soluble groups can increase its fat-soluble or water-soluble abilities, thus improving the bioavailability. The structure modification includes alkylation, acylation, sulfonation,glycosidation  of hydroxyl groups and the formation of the metal complex.
    The effects of naringenin including: anti-bacterial, anti-inflammatory, antioxidant, cough expectorant,decreasing blood fat, anti-cancer and anti-tumor, antispasmodic, scavenging free radicals, prevention and treatment of liver disease, inhibition of platelet aggregation, anti-atherosclerosis and others , which can be widely used in medicine, food and other fields.
    1. Antibacterial: it has a strong antibacterial effect on Staphylococcus aureus, Escherichia coli, Shigella dysenteriae, and Salmonella typhi. Naringenin also has effect on fungi  , 1000ppm is sprayed onto the rice, blast fungus infection can be reduced 40-90%,and it is not toxic to livestock and humans.
    2. Anti-inflammatory: intraperitoneal injection of 20mg/kg per day for rats can inhibit the inflammatory process which caused by wool ball implantation.
    3. Anticancer:  it displays action in L1210 leukemia and sarcomas in rats.
    4. Antispasmodic and gallbladder: among the flavonoids,it has stronger effects. Naringenin has a strong effect on increasing bile secretion in experimental animals.
  • Application It has anti-bacterial, anti-inflammatory, anti-cancer, antispasmodic and choleretic effects.
  • Chemical Properties beige-brown powder
  • Uses The aglucon of Naringin. Inhibitory mechanism of Naringenin against carcinogenic acrylamide formation and nonenzymic browning in Maillard model reactions
  • Uses antiulcer, antioxidant, immunomodulator, cholesterol lowering
  • Purification Methods Crystallise it from EtOH or aqueous EtOH. It has UV: at 290nm (EtOH). The S(-)-enantiomer (natural form) has m 255-256o (from EtOH) and [] D -28.0o (c 2, EtOH), [] D -35.2o (c 1, pyridine).
Naringenin Preparation Products And Raw materials
Raw materials
Preparation Products
Global(343)Suppliers
  • Supplier:
    Henan Tianfu Chemical Co.,Ltd.
  • Tel:0371-55170693
  • Fax:0371-55170693
  • Email:info@tianfuchem.com
  • Country:CHINA
  • ProdList:22610
  • Advantage:55
  • Supplier:
    Hangzhou FandaChem Co.,Ltd.
  • Tel:008615858145714
  • Fax:+86-571-56059825
  • Email:fandachem@gmail.com
  • Country:CHINA
  • ProdList:8869
  • Advantage:55
  • Supplier:
    career henan chemical co
  • Tel:+86-371-86658258
  • Fax:
  • Email:sales@coreychem.com
  • Country:CHINA
  • ProdList:29992
  • Advantage:58
480-41-1, NaringeninRelated Search:
  • naringenine
  • naringetol
  • 4’,5,7-trihydroxy-flavanon
  • S-Dihydrogenistein
  • NSC 34875
  • NSC 11855
  • (S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-ben
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (S)-
  • 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-chromanone
  • 5',7-trihydroxyflavanone
  • flavanone naringenin
  • Flavanone, 4',5,7-trihydroxy-
  • NARINGENIN-CMPD
  • pelargidanon
  • (2S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H- 1-benzopyran-4-one,99%e.e.
  • NARINGENIN hplc
  • NARINGENIN (4'',5,7-TRIHYDROXYFLAVANONE)
  • NARINGENIN WITH HPLC
  • 5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one
  • (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
  • salipurol
  • salipurpol
  • 5,7,4'-TRIHYDROXYFLAVANONE
  • 5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)CHROMAN-4-ONE
  • (+/-)-4',5,7-TRIHYDROXYFLAVANONE
  • 4',5,7-TRIHYDROXYFLAVANONE
  • (+/-)-2,3-DIHYDRO-5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE
  • TIMTEC-BB SBB006461
  • (+/-)-NARINGENIN
  • NARINGENIN
  • 4',5,7-Trihydroxyflavanone, Naringetol, Salipurpol,
  • (S)-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone
  • NARIGENIN
  • (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
  • Naringenin,Naringen,4',5,7-Trihydroxyflavanone
  • (2S)-Naringenin
  • 4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2S)-
  • (2S)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • (2S)-2α-(4-Hydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one
  • 4',5,7-TrihydroxyflavanoneNaringenin
  • (s)-naringenin
  • 3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-(s)-4h-1-benzopyran-4-on
  • Derivative of
  • (2R)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-chromen-4-one
  • 4'',5,7-Trihydroxyflavanone,naringetol
  • (S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)chroMan-4-one
  • Nano Liposomal naringetol
  • ringenin
  • 7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one
  • Nano Liposomal Naringenin
  • (s)-Naringenin 480-41-1
  • Naringenin fandachem
  • 480-41-1
  • C41H46O21
  • C42H48O22
  • Enzyme Inhibitors
  • Chemopreventive Agents
  • Cancer Research