Chemical Properties
White crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Fraxinuschinensis Roxb.
Uses
Dimethylfraxetin has a bactericidal, anti-inflammatory, anti-radiation damage, and immune-enhancing effects.
Definition
ChEBI: 6,7,8-trimethoxy-1-benzopyran-2-one is a member of coumarins.
Biological Activity
Dimethylfraxetin is a Carbonic anhydrase inhibitor with a Ki of 0.0097 μM.
in vitro
At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study .
target
Ki: 0.0097 μM (Carbonic anhydrase)