Dehydroepiandrosterone enanthate

Originator

Prasterone,Schering

Uses

Prasterone Enanthate is used in preparation of DHEA enanthates for treating/improving adrenal hormonal balance, immune system function, adipose tissue reduction, skeletal muscle growth, bloating reduction, recovery from training, and increasing strength.

Manufacturing Process

A mixture of 10.0 g of dehydro-epi-androsterone, 40 ml of pyridine and 20 ml of oenanthic acid anhydride was warmed for 2 h on a steam bath. About 10 ml of water were added and the mixture was warmed for a further 30 min. The reaction mixture was then subjected to a steam distillation. The resulting mixture was extracted with ether and the extract was successively washed with dilute sodium hydroxide solution, sodium carbonate solution and water.
The solution was dried over sodium sulfate and exaporated. 13.6 g of crude dehydro-epiandrosterone-3-oenanthate were obtained, melting point 70°-72°C (recrystallisation from methanol).

Therapeutic Function

Glucocorticoid