Uses
Anthelmintic(veterinary).
Definition
ChEBI: Naftalofos is an organic heterotricyclic compound. It has a role as an anthelminthic drug.
brand name
Maretin (Bayer Animal Health).
Mechanism of action
Acetylcholinesterase (AChE) inhibitor.
Synthesis
Naftalofos is synthesised through a multi-step chemical process that
begins with the preparation of O-ethyl phenylphosphonothioic acid, which
serves as the phosphorus-containing core. This intermediate is then
reacted with 2-naphthol, a hydroxylated aromatic compound, via
esterification, forming the characteristic O-naphthyl linkage. After the
coupling step, the crude product undergoes purification to isolate.
Pesticide Type
Insecticide; Veterinary substance
