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Desoxycorticosterone

Desoxycorticosterone Structure
Desoxycorticosterone
  • CAS No.64-85-7
  • Chemical Name:Desoxycorticosterone
  • CBNumber:CB4314147
  • Molecular Formula:C21H30O3
  • Formula Weight:330.46
  • MOL File:64-85-7.mol
Desoxycorticosterone Property
  • Melting point: :138-144 °C
  • alpha  :184 º (c=1, C2H5OH)
  • Boiling point: :407.89°C (rough estimate)
  • Density  :1.0998 (rough estimate)
  • refractive index  :1.5192 (estimate)
  • Flash point: :9℃
  • storage temp.  :-20°C
  • pka :12.98±0.10(Predicted)
  • Water Solubility  :slightly soluble
  • Merck  :13,2917
  • BRN  :2062123
  • CAS DataBase Reference :64-85-7(CAS DataBase Reference)
  • EWG's Food Scores :1
  • FDA UNII :40GP35YQ49
  • NIST Chemistry Reference :Deoxycorticosterone(64-85-7)
  • EPA Substance Registry System :Deoxycorticosterone (64-85-7)
Safety
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal wordDanger
  • Hazard statements H225-H301+H311+H331-H370-H351-H373
  • Precautionary statements P281-P210-P260-P280-P301+P310-P311
Desoxycorticosterone Price More Price(8)
  • Brand: Sigma-Aldrich
  • Product number: D-105
  • Product name : 11-Deoxycorticosterone solution
  • Purity: 
  • Packaging: 105-1ml
  • Price: $96.8
  • Updated: 2020/08/18
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: D-105
  • Product name : 11-Deoxycorticosterone solution
  • Purity: 100?μg/mL in methanol, ampule of 1?mL, certified reference material, Cerilliant?
  • Packaging: 1 mL
  • Price: $99.9
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Sigma-Aldrich
  • Product number: D6875
  • Product name : 21-Hydroxyprogesterone
  • Purity: ≥97% (HPLC)
  • Packaging: 1g
  • Price: $323
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 22916
  • Product name : 11-deoxy Corticosterone
  • Purity: ≥95%
  • Packaging: 25mg
  • Price: $43
  • Updated: 2021/03/22
  • Buy: Buy
  • Brand: Cayman Chemical
  • Product number: 22916
  • Product name : 11-deoxy Corticosterone
  • Purity: ≥95%
  • Packaging: 50mg
  • Price: $82
  • Updated: 2021/03/22
  • Buy: Buy

Desoxycorticosterone Chemical Properties,Usage,Production

  • Chemical Properties white to creamy-white crystalline powder
  • Uses A mineralocorticoid that occurs in adrenal cortex. It acts as a precursor to Aldosterone (A514700).
  • Uses Antiinflammatory;Corticoide
  • Definition ChEBI: A mineralocorticoid that is progesterone substituted at position 21 by a hydroxy group.
  • Hazard Toxic.
  • Mechanism of action Desoxycorticosterone causes an increase in reabsorption of sodium ions and excretion of potassium ions from the renal tubules, which leads to increased tissue hydrophilicity. This facilitates an elevated volume of plasma and increased arterial pressure. Muscle tonicity and work capability are increased. It is used for an insufficiency of function of the adrenal cortex, myasthenia, asthenia, adynamia, and overall muscle weakness.
  • Chemical Synthesis Desoxycorticosterone, 21-hydroxypregn-4-en-3,20-dione acetate (27.2.6), is synthesized in a number of ways, the easiest of which being iodination of progesterone at C21 in the methyl group, and subsequent reaction of the resulting iodo-derivative 27.2.5 with potassium acetate, which leads to formation of the desired desoxycorticosterone in the form of the acetate (27.2.6) .

  • Purification Methods Crystallise 11-deoxycorticosterone from diethyl ether. [Schindler et al. Helv Chim Acta 24 360 1941, Steiger & Reichstein Helv Chim Acta 20 1164 1937.]
Desoxycorticosterone Preparation Products And Raw materials
Raw materials
Preparation Products
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64-85-7, DesoxycorticosteroneRelated Search:
  • Corthormon
  • Corticosterone, 11-deoxy-
  • Deoxycortone
  • Pregn-4-en-21-ol-3,20-dione
  • Pregn-4-ene-3,20-dione, 21-hydroxy-
  • Progesterone, 21-hydroxy-
  • deoxycorticosterone crystalline
  • Desoxycorton
  • 21-HYDROXYPROGESTERON VETRANAL, 250 MG
  • 17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
  • HYDROXYPROGESTERONE, 21-(RG)
  • Reichstein Q, 11-Deoxycorticosterone, 11-Desoxycorticosterone, 21-Hydroxy-4-pregnene-3,20-dione, 4-Pregnen-21-ol-3,20-dione, Cortexone, Desoxycortone, DOC, Kendalls desoxy compound B
  • Deoxycorticosterone Propionate
  • DOC【steroid】
  • DesoxycorticosteroneDeoxycorticosterone
  • 21-Hydroxy-3,20-dioxopregn -4-ene
  • 21-Hydroxy-4-pregnane-3,20-dione
  • CORTEXONE
  • DELTA4-PREGNEN-21-OL-3,20-DIONE
  • DEOXYCORTICOSTERONE
  • DESOXYCORTICOSTERONE
  • DESOXYCORTONE
  • DOC
  • HYDROXYPROGESTERONE, 21-
  • KENDALL'S DESOXY COMPOUND B
  • 4-PREGNENE-21-OL-3,20-DIONE
  • 4-PREGNEN-21-OL-3,20-DIONE
  • 11-DESOXYCORTICOSTERONE
  • 11-DEOXYCORTICOSTERONE
  • 21-HYDROXY-4-PREGNENE-3,20-DIONE
  • 21-hydroxypregn-4-ene-3,20-dione
  • 21-HYDROXYPROGESTERONE
  • 'REICHSTEIN Q'
  • REICHSTEIN'S COMPOUND ''Q''
  • REICHSTEIN'S SUBSTANCE Q
  • (8S,10R,13S,17S)-17-(2-Hydroxy-acetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
  • 11-Dehydroxycorticosterone
  • 21-Hydroxypregn-4-en-3,20-dione
  • 21-hydroxy-progesteron
  • Desoxycorticosterone Solution, 100ppm
  • 11-Deoxycorticosterone solution
  • Corticosterone Impurity 5
  • 11-Deoxycorticosterone-2,3,4-13C3 solution 100 mug/mL in methanol, >=99 atom % 13C, >=98% (CP)
  • Desoxycorticosterone USP/EP/BP
  • 64-85-7
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Steroids