Chemical Properties
2-Diethylaminoethylchloride hydrochloride is colourless to beige crystals
Uses
2-Chloro-N,N-diethylethylamine hydrochloride (65% in water) (DEC 65) is used as intermediate for the syntheses of pharmaceuticals (e.g. amiodarone, butetamate citrate, flurazepam and naftidrofuryl). Product Data Sheet
Uses
2-Chloro-
N,N-diethylethylamine hydrochloride can be used as an alkylating reagent for the synthesis of:
- Substituted oxindole derivatives to be used as growth hormone secretagogs.
- 1-Substituted-5,6-dinitrobenzimidazoles with antimicrobial and antiprotozoal activities.
- Thiophene containing triarylmethane (TRAM) derivatives to be used as antitubercular agents.
- Tris(2-(diethylamino)ethyl)amine to be used as a catalyst in combination with CuBr (Et6TREN/CuBr) for atom transfer radical polymerization of n-butyl acrylate.
It can also be used for the derivatization of chitosan to incorporate aminofunctionality onto it at C-6 position.
Uses
2-Diethylaminoethylchloride hydrochloride is used as intermediate for the syntheses of pharmaceuticals (e.g. amiodarone, butetamate citrate, flurazepam and naftidrofuryl). Product Data Sheet
Purification Methods
Crystallise the salt from absolute MeOH (to remove highly coloured impurities). [Beilstein 4 III 240.]
