Chemical Properties
Colourless to light yellow oil
Uses
18:1-2:0 DG (1-oleoyl-2-acetyl-
sn-glycerol) has been used as a diacyl glycerol (DAG) analog to test its impact on DAG-sensitive channels in thalamocortical (TC) neurons. It may be used as an internal standard for retention time calibration in ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UPLC-QTOF MS)?for blood sample lipid quantification. It may also be used as a protein kinase C (PKC) activator in adrenal glands.
Uses
Activator of phospholipid-dependent protein kinase C; and stimulator of secretion and aggregation in blood platelets.x
Definition
ChEBI: 1-Oleoyl-2-acetyl-sn-glycerol is a 1,2-diglyceride.
General Description
18:1-2:0 DG, also called 1-oleoyl-2-acetyl-
sn-glycerol (OADG), is a synthetic analog of diacyl glycerol (DAG) and is membrane permeable.
Biochem/physiol Actions
1-Oleoyl-2-acetyl-sn-glycerol is a synthetic, cell permeable diacylglycerol analog. It is often used as an activator of calcium-dependent protein kinase C (PKC).
