Description
Olaquindox is an antibacterial derivative of quinoxaline,
used as a growth promoter for pigs.
Description
Olaquindox is an antibiotic and a swine growth regulator.
In vivo, olaquindox (100 mg/kg) decreases
E. coli-induced diarrhea and the number of intraepithelial lymphocytes in the ileum and increases body weight in geld piglets. Olaquindox induces bleeding, intramuscular edema, vacuolar degeneration, and deformation of renal tubules in
C. carpio. It decreases mean body weight and increases the number of dead fetuses in pregnant rats when administered at a dose of 110 mg/kg and increases the number of external deformities, including bent tail, craniorachischisis, exencephaly, and anophthalmia in rat pups born to exposed pregnant mothers. Formulations containing olaquindox have been used as growth promoting agents in bovine livestock.
Chemical Properties
Pale Yellow Crystalline Solid
Uses
Olaquindox is a growth promotor in pig-breeding; acts as a chemotherapeutic agent prophylactically used to lower the frequency of bacterial enteritis in pigs.
Uses
It can be
found in Bayo-N-Ox and Proquindox and numerous
oilier pig feed. It is a photosensitizer and forms a
reactive oxyziridine on exposure to light. It can also
induce photo allergie contact dermatitis and persistent
light reactions in pig breeders.
Definition
ChEBI: Olaquindox [BAN:INN] is a quinoxaline derivative.
Contact allergens
Olaquindox is an antibacterial agent derivative of quinoxaline,
used as a growth promoter of pigs. It can be
found in Bayo-N-Ox? and Proquindox? and numerous
other pig feeds. It is a photosensitizer that forms reactive
photoproducts on light exposure. It can induce photoallergic
contact dermatitis and persistent light reactions.
