Description
11-
deoxy PGF
2α is a synthetic analog of PGF
2α. It is a more potent agonist than PGF
2α at inducing smooth muscle contractions of rabbit aorta, dog saphenous vein, and guinea pig trachea. It is approximately 20% less potent than U-
46619.
References
[1] Dadi PK,et al., Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx. ACS Chem Neurosci. 2017 Mar 15;8(3):558-568. DOI:
10.1021/acschemneuro.6b00301