4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]

Chemical Properties

White or almost white, crystalline powder.

Uses

Suxibuzone is a prodrug of the non steroidal anti inflammatory drug phenylbutazone. It is a drug used for joint and muscular pain.

Uses

analgesic, antipyretic, antiinflammatory

Definition

ChEBI: A pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses.

brand name

Calibene;Danalon om;Danilon;Flamilon;Flofos.

World Health Organization (WHO)

Suxibuzone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1974 for the treatment of rheumatic disorders. As it is structurally related to phenylbutazone, it is subjected to rigorously restricted indications by some national regulatory authorities. See WHO comment for phenylbutazone.

Biochem/physiol Actions

A prodrug of phenylbutazone.