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Benidipine

Benidipine Structure
Benidipine
  • CAS No.105979-17-7
  • Chemical Name:Benidipine
  • CBNumber:CB2131201
  • Molecular Formula:C28H31N3O6
  • Formula Weight:505.56
  • MOL File:105979-17-7.mol
Benidipine Property
Hazard and Precautionary Statements (GHS)
  • Symbol(GHS)
  • Signal word
  • Hazard statements
  • Precautionary statements
Benidipine Price More Price(6)
  • Brand: TRC
  • Product number: B157508
  • Product name : racBenidipine
  • Purity: 
  • Packaging: 0.5mg
  • Price: $45
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: American Custom Chemicals Corporation
  • Product number: API0002106
  • Product name : CONIEL
  • Purity: 95.00%
  • Packaging: 100MG
  • Price: $693
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: Medical Isotopes, Inc.
  • Product number: 18512
  • Product name : Benidipine
  • Purity: 
  • Packaging: 25 mg
  • Price: $1500
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: American Custom Chemicals Corporation
  • Product number: API0002106
  • Product name : CONIEL
  • Purity: 95.00%
  • Packaging: 1G
  • Price: $1501.5
  • Updated: 2021/12/16
  • Buy: Buy
  • Brand: AvaChem
  • Product number: 3003B
  • Product name : Benidipine
  • Purity: 
  • Packaging: 100mg
  • Price: $89
  • Updated: 2021/12/16
  • Buy: Buy

Benidipine Chemical Properties,Usage,Production

  • Enzyme inhibitor This oral, once-daily antihypertensive agent (FW = 505.57 g/mol; CAS 105979-17-7), also known by its code name KW-3049, trade name Coniel?, and systematic name O -methyl,O -[(3R)-1-(phenylmethyl)piperidin-3-yl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, is a dihydropyridine-class calcium ion blocker that is effective against L-, N-, and T-channels, with potent and selective inhibitory action on cardiac slow calcium channels. Benidipine bound stereospecifically to nitrendipine binding sites of rat myocardium with high affinity (Ki = 0.13 nM) and to the rat brain a1-adrenergic receptor (Ki = 1.2 μM). KW-3049 exhibited no remarkable binding affinity to a2 adrenergic, b-adrenergic, D2 dopamine, H1 histamine, S2 serotonin, A1 adenosine, A2 adenosine and muscarinic cholinergic receptors at 100 μM.
Benidipine Preparation Products And Raw materials
Raw materials
Preparation Products
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105979-17-7, BenidipineRelated Search:
  • (R*,R*)-(±)-(3,5-Pyridinedicarboxylic acid 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-methyl 1- (phenylmethyl)-3-piperidinyl ester monohydrochloride
  • 3,5-Pyridinedicarboxylicacid, 1,4-dihydro-2,6-diMethyl-4-(3-nitrophenyl)-, 3-Methyl5-[(3R)-1-(phenylMethyl)-3-piperidinyl] ester, (4R)-rel-
  • NACADIPINE
  • BENIDIPINE
  • BENIDIPINE HCL
  • CAPADIPINE
  • CONIEL
  • KW-3049
  • 5-O-[(3R)-1-benzylpiperidin-3-yl] 3-O-methyl (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl (3R)-1-(phenylmethyl)-3-piperidinyl ester, (4R)-rel-
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 1-(phenylmethyl)-3-piperidinyl ester, (R*,R*)-
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 1-(phenylmethyl)-3-piperidinyl ester, (R*,R*)-(+-)-
  • (+/-)-(R*)-3-((R*)-1-Benzyl-3-piperidyl) methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5-pyridinedicarboxylate
  • (R^<*>^,R^<*>^)-(±)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3,5-pyridinedicarboxylic acid methyl(R^<*>^)-1-BenzyI-3-piperidylester
  • (4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-methyl 5-[(3R)-1-benzylpiperidin-3-yl] ester
  • (4R)-2,6-Dimethyl-1,4-dihydro-4-(3-nitrophenyl)pyridine-3,5-dicarboxylic acid 3-methyl 5-[(3R)-1-benzylpiperidin-3-yl] ester
  • (4R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O3-methyl ester O5-[(3R)-1-(phenylmethyl)-3-piperidinyl] ester
  • rac Benidipine
  • Benidipine USP/EP/BP
  • 105979-17-7
  • C28H31N3O6HCl
  • Aromatics
  • Chiral Reagents
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Pharmaceutical