Chemical Properties
white crystalline powder
Uses
Reactant for:
- Hydroxymethylation reactions
- Radical carbonylation reactions
- Reduction reactions (reductant)
Uses
Tetrabutylammonium Cyanoborohydride is used in preparation method of novel biomass plastic material.
Application
Tetrabutylammonium cyanoborohydride (TBAC) is used as a selective, mild reducing reagent for aldehydes, conjugated aldehydes and ketones, alkyl iodides and bromides; useful for reductive
aminations of aldehydes and ketones in nonpolar solvents.
Preparation
Tetrabutylammonium cyanoborohydride is prepared from n-Bu4NHSO4 suspended in H2O, treated with Sodium Hydroxide and Sodium Cyanoborohydride, and
extracted into CH2Cl2; recrystallized from ethyl acetate. Other tetraalkylammonium derivatives are available (including polymersupported) or can be generated in situ from NaBH3CN and Aliquat 336.
reaction suitability
reagent type: reductant
