Tetrabutylammonium borohydride

Chemical Properties

white crystalline powder

Uses

Tetrabutylammonium Borohydride is a strong reducing agent used in the synthesis of hyperbranched polyglycerol grafting on the surface of silica-coated nanoparticles.

Purification Methods

Purify it by recrystallisation from EtOAc followed by careful drying under vacuum at 50-60o. Samples purified in this way showed no signs of loss of active H after storage at room temperature for more than 1year. Nevertheless samples should be stored at ca 6o in tightly stoppered bottles if kept for long periods. It is soluble in CH2Cl2. [Raber & Guida J Org Chem 41 690 1976, Br.ndstr.m et al. Tetrahedron Lett 3173 1972.]